Identity
HGNC
LOCATION
11q12.3
LOCUSID
ALIAS
ALP,ALP1,CRASH
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 80150
MIM: 609212
HGNC: 16448
Ensembl: ENSG00000162174
Variants:
dbSNP: 80150
ClinVar: 80150
TCGA: ENSG00000162174
COSMIC: ASRGL1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36572570 | 2023 | ASRGL1 downregulation suppresses hepatocellular carcinoma tumorigenesis in a CDK1-dependent manner. | 0 |
| 36842323 | 2023 | l-Asparaginase regulates mTORC1 activity via a TSC2-dependent pathway in pancreatic beta cells. | 1 |
| 36572570 | 2023 | ASRGL1 downregulation suppresses hepatocellular carcinoma tumorigenesis in a CDK1-dependent manner. | 0 |
| 36842323 | 2023 | l-Asparaginase regulates mTORC1 activity via a TSC2-dependent pathway in pancreatic beta cells. | 1 |
| 32434038 | 2020 | The role of the quaternary structure in the activation of human L-asparaginase. | 3 |
| 32434038 | 2020 | The role of the quaternary structure in the activation of human L-asparaginase. | 3 |
| 29096882 | 2018 | Asparaginase-like protein 1 is an independent prognostic marker in primary endometrial cancer, and is frequently lost in metastatic lesions. | 8 |
| 29486992 | 2018 | Combined ASRGL1 and p53 immunohistochemistry as an independent predictor of survival in endometrioid endometrial carcinoma. | 9 |
| 29684683 | 2018 | Brain-related proteins as potential CSF biomarkers of Alzheimer's disease: A targeted mass spectrometry approach. | 38 |
| 29767260 | 2018 | RNAi‑mediated downregulation of asparaginase‑like protein 1 inhibits growth and promotes apoptosis of human cervical cancer line SiHa. | 4 |
| 29096882 | 2018 | Asparaginase-like protein 1 is an independent prognostic marker in primary endometrial cancer, and is frequently lost in metastatic lesions. | 8 |
| 29486992 | 2018 | Combined ASRGL1 and p53 immunohistochemistry as an independent predictor of survival in endometrioid endometrial carcinoma. | 9 |
| 29684683 | 2018 | Brain-related proteins as potential CSF biomarkers of Alzheimer's disease: A targeted mass spectrometry approach. | 38 |
| 29767260 | 2018 | RNAi‑mediated downregulation of asparaginase‑like protein 1 inhibits growth and promotes apoptosis of human cervical cancer line SiHa. | 4 |
| 26780688 | 2016 | Intramolecular Cleavage of the hASRGL1 Homodimer Occurs in Two Stages. | 7 |
Citation
Dessen P
ASRGL1 (asparaginase and isoaspartyl peptidase 1)
Atlas Genet Cytogenet Oncol Haematol. 2009-08-01
Online version: http://atlasgeneticsoncology.org/gene/51011/asrgl1
