| Nomenclature |
|---|
| HGNC (Hugo) | ATF6B 2349 |
| Cards |
|---|
| Entrez_Gene (NCBI) | ATF6B 1388 activating transcription factor 6 beta |
| Aliases | CREB-RP; CREBL1; G13 |
| GeneCards (Weizmann) | ATF6B |
| Ensembl hg19 (Hinxton) | ENSG00000213676 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000213676 [Gene_View] ENSG00000213676 [Sequence] chr6:32115268-32128240 [Contig_View] ATF6B [Vega] |
| ICGC DataPortal | ENSG00000213676 |
| TCGA cBioPortal | ATF6B |
| AceView (NCBI) | ATF6B |
| Genatlas (Paris) | ATF6B |
| WikiGenes | 1388 |
| SOURCE (Princeton) | ATF6B |
| Genetics Home Reference (NIH) | ATF6B |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | ATF6B - chr6:32115268-32128240 - 6p21.32 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | ATF6B - 6p21.32 [Description] (hg19-Feb_2009) |
| GoldenPath | ATF6B - 6p21.32 [CytoView hg19] ATF6B - 6p21.32 [CytoView hg38] |
| ImmunoBase | ENSG00000213676 |
| Mapping of homologs : NCBI | ATF6B [Mapview hg19] ATF6B [Mapview hg38] |
| OMIM | 600984 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AK000928 BC008394 BC077075 BT007042 U31903 |
| RefSeq transcript (Entrez) | NM_001136153 NM_004381 |
| RefSeq genomic (Entrez) | NC_000006 NG_033940 NT_113891 NT_167245 NT_167247 |
| Consensus coding sequences : CCDS (NCBI) | ATF6B |
| Cluster EST : Unigene | Hs.42853 [ NCBI ] |
| CGAP (NCI) | Hs.42853 |
| Alternative Splicing Gallery | ENSG00000213676 |
| Gene Expression | ATF6B [ NCBI-GEO ] ATF6B [ EBI - ARRAY_EXPRESS ]
ATF6B [ SEEK ] ATF6B [ MEM ] |
| Gene Expression Viewer (FireBrowse) | ATF6B [ Firebrowse - Broad ] |
| SOURCE (Princeton) | Expression in : [Datasets] [Normal Tissue Atlas] [carcinoma Classsification] [NCI60] |
| Genevestigator | Expression in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 1388 |
| GTEX Portal (Tissue expression) | ATF6B |
| Human Protein Atlas | ENSG00000213676-ATF6B [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | Q99941 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | Q99941 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | Q99941 |
| Splice isoforms : SwissVar | Q99941 |
| PhosPhoSitePlus | Q99941 |
| Domaine pattern : Prosite (Expaxy) | BZIP (PS50217) BZIP_BASIC (PS00036) |
| Domains : Interpro (EBI) | ATF6B bZIP |
| Domain families : Pfam (Sanger) | bZIP_1 (PF00170) |
| Domain families : Pfam (NCBI) | pfam00170 |
| Domain families : Smart (EMBL) | BRLZ (SM00338) |
| Conserved Domain (NCBI) | ATF6B |
| DMDM Disease mutations | 1388 |
| Blocks (Seattle) | ATF6B |
| Superfamily | Q99941 |
| Human Protein Atlas [tissue] | ENSG00000213676-ATF6B [tissue] |
| Peptide Atlas | Q99941 |
| HPRD | 02992 |
| IPI | IPI00004084 IPI00221087 IPI00514304 IPI00791919 IPI00847851 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | Q99941 |
| IntAct (EBI) | Q99941 |
| FunCoup | ENSG00000213676 |
| BioGRID | ATF6B |
| STRING (EMBL) | ATF6B |
| ZODIAC | ATF6B |
| Ontologies - Pathways |
|---|
| QuickGO | Q99941 |
| Ontology : AmiGO | RNA polymerase II distal enhancer sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity protein binding nucleus nucleolus endoplasmic reticulum membrane Golgi apparatus transcription, DNA-templated signal transduction integral component of endoplasmic reticulum membrane integral component of endoplasmic reticulum membrane protein-DNA complex cAMP response element binding ATF6-mediated unfolded protein response transcription regulatory region DNA binding positive regulation of transcription by RNA polymerase II RNA polymerase II transcription factor complex negative regulation of ATF6-mediated unfolded protein response positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress |
| Ontology : EGO-EBI | RNA polymerase II distal enhancer sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity protein binding nucleus nucleolus endoplasmic reticulum membrane Golgi apparatus transcription, DNA-templated signal transduction integral component of endoplasmic reticulum membrane integral component of endoplasmic reticulum membrane protein-DNA complex cAMP response element binding ATF6-mediated unfolded protein response transcription regulatory region DNA binding positive regulation of transcription by RNA polymerase II RNA polymerase II transcription factor complex negative regulation of ATF6-mediated unfolded protein response positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress |
| NDEx Network | ATF6B |
| Atlas of Cancer Signalling Network | ATF6B |
| Wikipedia pathways | ATF6B |
| Orthology - Evolution |
|---|
| OrthoDB | 1388 |
| GeneTree (enSembl) | ENSG00000213676 |
| Phylogenetic Trees/Animal Genes : TreeFam | ATF6B |
| HOGENOM | Q99941 |
| Homologs : HomoloGene | ATF6B |
| Homology/Alignments : Family Browser (UCSC) | ATF6B |
| Gene fusions - Rearrangements |
|---|
| Fusion : Quiver | ATF6B |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | ATF6B [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | ATF6B |
| dbVar | ATF6B |
| ClinVar | ATF6B |
| 1000_Genomes | ATF6B |
| Exome Variant Server | ATF6B |
| ExAC (Exome Aggregation Consortium) | ENSG00000213676 |
| GNOMAD Browser | ENSG00000213676 |
| Varsome Browser | ATF6B |
| Genetic variants : HAPMAP | 1388 |
| Genomic Variants (DGV) | ATF6B [DGVbeta] |
| DECIPHER | ATF6B [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | ATF6B |
| Mutations |
|---|
| ICGC Data Portal | ATF6B |
| TCGA Data Portal | ATF6B |
| Broad Tumor Portal | ATF6B |
| OASIS Portal | ATF6B [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | ATF6B [overview] [genome browser] [tissue] [distribution] |
| Somatic Mutations in Cancer : COSMIC3D | ATF6B |
| Mutations and Diseases : HGMD | ATF6B |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| BioMuta | search ATF6B |
| DgiDB (Drug Gene Interaction Database) | ATF6B |
| DoCM (Curated mutations) | ATF6B (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | ATF6B (select a term) |
| intoGen | ATF6B |
| Cancer3D | ATF6B(select the gene name) |
| Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 600984 |
| Orphanet | |
| DisGeNET | ATF6B |
| Medgen | ATF6B |
| Genetic Testing Registry | ATF6B
|
| NextProt | Q99941 [Medical] |
| TSGene | 1388 |
| GENETests | ATF6B |
| Target Validation | ATF6B |
| Huge Navigator |
ATF6B [HugePedia] |
| snp3D : Map Gene to Disease | 1388 |
| BioCentury BCIQ | ATF6B |
| ClinGen | ATF6B |
| Clinical trials, drugs, therapy |
|---|
| Chemical/Protein Interactions : CTD | 1388 |
| Chemical/Pharm GKB Gene | PA164716250 |
| Clinical trial | ATF6B |
| Miscellaneous |
|---|
| canSAR (ICR) | ATF6B (select the gene name) |
| DataMed Index | ATF6B |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 32 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| CoreMine | ATF6B |
| EVEX | ATF6B |
| GoPubMed | ATF6B |
| iHOP | ATF6B |
