ATG16L2 (autophagy related 16 like 2)

2014-08-01  

Identity

HGNC
LOCATION
11q13.4
LOCUSID
ALIAS
ATG16B,WDR80
FUSION GENES

Other Information

Locus ID:

NCBI: 89849
MIM: 618716
HGNC: 25464
Ensembl: ENSG00000168010

Variants:

dbSNP: 89849
ClinVar: 89849
TCGA: ENSG00000168010
COSMIC: ATG16L2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000168010ENST00000321297Q8NAA4
ENSG00000168010ENST00000435507F5GWM4
ENSG00000168010ENST00000534905F5GWZ9
ENSG00000168010ENST00000535830H0YFG0
ENSG00000168010ENST00000537837H0YFC3
ENSG00000168010ENST00000538973H0YG67
ENSG00000168010ENST00000540222H0YG45
ENSG00000168010ENST00000540567H0YGJ8
ENSG00000168010ENST00000541367H0YF72
ENSG00000168010ENST00000541554H0YFZ7
ENSG00000168010ENST00000541999H0YGE3
ENSG00000168010ENST00000544490F5H7B6

Expression (GTEx)

0
50
100
150
200

Pathways

PathwaySourceExternal ID
Autophagy - animalKEGGko04140
Autophagy - animalKEGGhsa04140

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
238507132014Genome-wide association study of Crohn's disease in Koreans revealed three new susceptibility loci and common attributes of genetic susceptibility across ethnic populations.57
266633012016Identification of a Systemic Lupus Erythematosus Risk Locus Spanning ATG16L2, FCHSD2, and P2RY2 in Koreans.15
244061502014Autophagy-related gene16L2, a potential serum biomarker of multiple sclerosis evaluated by bead-based proteomic technology.10
294548632018Potentially Functional Variants of ATG16L2 Predict Radiation Pneumonitis and Outcomes in Patients with Non-Small Cell Lung Cancer after Definitive Radiotherapy.8
276113162016A functional variant of ATG16L2 is associated with Crohn's disease in the Chinese population.3
316922592019Potentially functional variants of autophagy-related genes are associated with the efficacy and toxicity of radiotherapy in patients with nasopharyngeal carcinoma.1

Citation

Dessen P

ATG16L2 (autophagy related 16 like 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54138/atg16l2