ATP5ME (ATP synthase membrane subunit e)

2018-02-01  

Identity

HGNC
LOCATION
4p16.3
LOCUSID
ALIAS
ATP5I,ATP5K

Other Information

Locus ID:

NCBI: 521
MIM: 601519
HGNC: 846
Ensembl: ENSG00000169020

Variants:

dbSNP: 521
ClinVar: 521
TCGA: ENSG00000169020
COSMIC: ATP5ME

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000169020ENST00000304312P56385

Pathways

PathwaySourceExternal ID
Oxidative phosphorylationKEGGko00190
Oxidative phosphorylationKEGGhsa00190
Metabolic pathwaysKEGGhsa01100
F-type ATPase, eukaryotesKEGGhsa_M00158
F-type ATPase, eukaryotesKEGGM00158
MetabolismREACTOMER-HSA-1430728
The citric acid (TCA) cycle and respiratory electron transportREACTOMER-HSA-1428517
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.REACTOMER-HSA-163200
Formation of ATP by chemiosmotic couplingREACTOMER-HSA-163210

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.17
166820022006F1F0-ATP synthase functions as a co-chaperone of Hsp90-substrate protein complexes.13
180608602008Atrazine binds to F1F0-ATP synthase and inhibits mitochondrial function in sperm.6
119394122001Antisense of ATP synthase subunit e inhibits the growth of human hepatocellular carcinoma cells.1

Citation

Dessen P

ATP5ME (ATP synthase membrane subunit e)

Atlas Genet Cytogenet Oncol Haematol. 2018-02-01

Online version: http://atlasgeneticsoncology.org/gene/57377/atp5me