Identity
HGNC
LOCATION
16p13.3
LOCUSID
ALIAS
ATP6C,ATP6L,ATPL,VATL,VPPC,Vma3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 527
MIM: 108745
HGNC: 855
Ensembl: ENSG00000185883
Variants:
dbSNP: 527
ClinVar: 527
TCGA: ENSG00000185883
COSMIC: ATP6V0C
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000185883 | ENST00000330398 | P27449 |
| ENSG00000185883 | ENST00000564973 | H3BNI4 |
| ENSG00000185883 | ENST00000565223 | H3BNI4 |
| ENSG00000185883 | ENST00000568562 | H3BMY0 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38481802 | 2024 | Impaired TFEB-mediated autophagy-lysosome fusion promotes tubular cell cycle G2/M arrest and renal fibrosis by suppressing ATP6V0C expression and interacting with SNAREs. | 1 |
| 38481802 | 2024 | Impaired TFEB-mediated autophagy-lysosome fusion promotes tubular cell cycle G2/M arrest and renal fibrosis by suppressing ATP6V0C expression and interacting with SNAREs. | 1 |
| 36074901 | 2023 | ATP6V0C variants impair V-ATPase function causing a neurodevelopmental disorder often associated with epilepsy. | 3 |
| 37161035 | 2023 | ATP6V0C gene variants were identified in individuals with epilepsy, with or without developmental delay. | 0 |
| 36074901 | 2023 | ATP6V0C variants impair V-ATPase function causing a neurodevelopmental disorder often associated with epilepsy. | 3 |
| 37161035 | 2023 | ATP6V0C gene variants were identified in individuals with epilepsy, with or without developmental delay. | 0 |
| 31840304 | 2020 | ATP6L promotes metastasis of colorectal cancer by inducing epithelial-mesenchymal transition. | 6 |
| 32291285 | 2020 | The viral protein U (Vpu)-interacting host protein ATP6V0C down-regulates cell-surface expression of tetherin and thereby contributes to HIV-1 release. | 5 |
| 31840304 | 2020 | ATP6L promotes metastasis of colorectal cancer by inducing epithelial-mesenchymal transition. | 6 |
| 32291285 | 2020 | The viral protein U (Vpu)-interacting host protein ATP6V0C down-regulates cell-surface expression of tetherin and thereby contributes to HIV-1 release. | 5 |
| 31554233 | 2019 | Vacuolar H(+)-ATPase Subunit V0C Regulates Aerobic Glycolysis of Esophageal Cancer Cells via PKM2 Signaling. | 9 |
| 31554233 | 2019 | Vacuolar H(+)-ATPase Subunit V0C Regulates Aerobic Glycolysis of Esophageal Cancer Cells via PKM2 Signaling. | 9 |
| 29138865 | 2018 | Silencing of vacuolar ATPase c subunit ATP6V0C inhibits the invasion of prostate cancer cells through a LASS2/TMSG1-independent manner. | 10 |
| 29138865 | 2018 | Silencing of vacuolar ATPase c subunit ATP6V0C inhibits the invasion of prostate cancer cells through a LASS2/TMSG1-independent manner. | 10 |
| 26110566 | 2015 | AGPAT9 suppresses cell growth, invasion and metastasis by counteracting acidic tumor microenvironment through KLF4/LASS2/V-ATPase signaling pathway in breast cancer. | 14 |
Citation
Dessen P
ATP6V0C (ATPase H+ transporting V0 subunit c)
Atlas Genet Cytogenet Oncol Haematol. 2009-06-01
Online version: http://atlasgeneticsoncology.org/gene/50975/atp6v0c
