AVPR1B (arginine vasopressin receptor 1B)

2014-11-01  

Identity

HGNC
LOCATION
1q32.1
LOCUSID
ALIAS
AVPR3,V1bR

Other Information

Locus ID:

NCBI: 553
MIM: 600264
HGNC: 896
Ensembl: ENSG00000198049

Variants:

dbSNP: 553
ClinVar: 553
TCGA: ENSG00000198049
COSMIC: AVPR1B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000198049ENST00000367126P47901

Expression (GTEx)

0
1
2
3
4
5
6
7
8
9

Pathways

PathwaySourceExternal ID
Calcium signaling pathwayKEGGko04020
Neuroactive ligand-receptor interactionKEGGko04080
Calcium signaling pathwayKEGGhsa04020
Neuroactive ligand-receptor interactionKEGGhsa04080
Vascular smooth muscle contractionKEGGhsa04270
Vascular smooth muscle contractionKEGGko04270
DiseaseREACTOMER-HSA-1643685
Disorders of transmembrane transportersREACTOMER-HSA-5619115
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR ligand bindingREACTOMER-HSA-500792
Class A/1 (Rhodopsin-like receptors)REACTOMER-HSA-373076
Peptide ligand-binding receptorsREACTOMER-HSA-375276
Vasopressin-like receptorsREACTOMER-HSA-388479
GPCR downstream signalingREACTOMER-HSA-388396
G alpha (q) signalling eventsREACTOMER-HSA-416476
Gastrin-CREB signalling pathway via PKC and MAPKREACTOMER-HSA-881907
SLC transporter disordersREACTOMER-HSA-5619102
Defective AVP causes neurohypophyseal diabetes insipidus (NDI)REACTOMER-HSA-5619099
Phospholipase D signaling pathwayKEGGko04072
Phospholipase D signaling pathwayKEGGhsa04072

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
198745742009Genetical genomic determinants of alcohol consumption in rats and humans.93
195982352009Genes related to sex steroids, neural growth, and social-emotional behavior are associated with autistic traits, empathy, and Asperger syndrome.92
195982352009Genes related to sex steroids, neural growth, and social-emotional behavior are associated with autistic traits, empathy, and Asperger syndrome.92
203517142011Poor replication of candidate genes for major depressive disorder using genome-wide association data.92
183840792008Combined effects of exonic polymorphisms in CRHR1 and AVPR1B genes in a case/control study for panic disorder.30
183840792008Combined effects of exonic polymorphisms in CRHR1 and AVPR1B genes in a case/control study for panic disorder.30
203685122010Association of polymorphisms in genes regulating the corticotropin-releasing factor system with antidepressant treatment response.30
155282112005A novel C-terminal motif is necessary for the export of the vasopressin V1b/V3 receptor to the plasma membrane.27
173183842007Dimerization between vasopressin V1b and corticotropin releasing hormone type 1 receptors.24
179091312007Evidence of an association between the vasopressin V1b receptor gene (AVPR1B) and childhood-onset mood disorders.19

Citation

Dessen P

AVPR1B (arginine vasopressin receptor 1B)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/60669/avpr1b