BAG2 (BAG cochaperone 2)

2006-10-01  

Identity

HGNC
LOCATION
6p12.1
LOCUSID
ALIAS
BAG-2,dJ417I1.2
FUSION GENES

Other Information

Locus ID:

NCBI: 9532
MIM: 603882
HGNC: 938
Ensembl: ENSG00000112208

Variants:

dbSNP: 9532
ClinVar: 9532
TCGA: ENSG00000112208
COSMIC: BAG2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000112208ENST00000370693O95816

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Pathways

PathwaySourceExternal ID
Protein processing in endoplasmic reticulumKEGGko04141
Protein processing in endoplasmic reticulumKEGGhsa04141
Cellular responses to stressREACTOMER-HSA-2262752
Cellular response to heat stressREACTOMER-HSA-3371556
Regulation of HSF1-mediated heat shock responseREACTOMER-HSA-3371453

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
382367732024Recruitment of BAG2 to DNAJ-PKAc scaffolds promotes cell survival and resistance to drug-induced apoptosis in fibrolamellar carcinoma.1
382367732024Recruitment of BAG2 to DNAJ-PKAc scaffolds promotes cell survival and resistance to drug-induced apoptosis in fibrolamellar carcinoma.1
365939502023BAG2 drives chemoresistance of breast cancer by exacerbating mutant p53 aggregate.7
365939502023BAG2 drives chemoresistance of breast cancer by exacerbating mutant p53 aggregate.7
349697632022Helicobacter pylori Targets in AGS Human Gastric Adenocarcinoma: In Situ Proteomic Profiling and Systematic Analysis.3
353678232022c-MYC-USP49-BAG2 axis promotes proliferation and chemoresistance of colorectal cancer cells in vitro.8
356127802022BAG2 prevents Tau hyperphosphorylation and increases p62/SQSTM1 in cell models of neurodegeneration.1
349697632022Helicobacter pylori Targets in AGS Human Gastric Adenocarcinoma: In Situ Proteomic Profiling and Systematic Analysis.3
353678232022c-MYC-USP49-BAG2 axis promotes proliferation and chemoresistance of colorectal cancer cells in vitro.8
356127802022BAG2 prevents Tau hyperphosphorylation and increases p62/SQSTM1 in cell models of neurodegeneration.1
332020882021Identification of BAG2 and Cathepsin D as Plasma Biomarkers for Parkinson's Disease.10
342575422021Bcl-2 Associated Athanogene 2 (BAG2) is Associated With Progression and Prognosis of Hepatocellular Carcinoma: A Bioinformatics-Based Analysis.6
332020882021Identification of BAG2 and Cathepsin D as Plasma Biomarkers for Parkinson's Disease.10
342575422021Bcl-2 Associated Athanogene 2 (BAG2) is Associated With Progression and Prognosis of Hepatocellular Carcinoma: A Bioinformatics-Based Analysis.6
324241432020LOXL1 confers antiapoptosis and promotes gliomagenesis through stabilizing BAG2.20

Citation

Dessen P

BAG2 (BAG cochaperone 2)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43159/bag2