BAG5 (BAG cochaperone 5)

2006-10-01  

Identity

HGNC
LOCATION
14q32.33
LOCUSID
ALIAS
BAG-5
FUSION GENES

Other Information

Locus ID:

NCBI: 9529
MIM: 603885
HGNC: 941
Ensembl: ENSG00000166170

Variants:

dbSNP: 9529
ClinVar: 9529
TCGA: ENSG00000166170
COSMIC: BAG5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000166170ENST00000299204Q9UL15
ENSG00000166170ENST00000299204A0A024R6M6
ENSG00000166170ENST00000337322Q9UL15
ENSG00000166170ENST00000445922Q9UL15
ENSG00000166170ENST00000445922A0A024R6M6
ENSG00000166170ENST00000557666G3V274

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
Cellular responses to stressREACTOMER-HSA-2262752
Cellular response to heat stressREACTOMER-HSA-3371556
Regulation of HSF1-mediated heat shock responseREACTOMER-HSA-3371453

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
381393592023Akt Is Controlled by Bag5 through a Monoubiquitination to Polyubiquitination Switch.0
381393592023Akt Is Controlled by Bag5 through a Monoubiquitination to Polyubiquitination Switch.0
325834302021Bcl-2-associated athanogene 5 overexpression attenuates catecholamine-induced vascular endothelial cell apoptosis.3
331866562021PRMT6 deficiency induces autophagy in hostile microenvironments of hepatocellular carcinoma tumors by regulating BAG5-associated HSC70 stability.12
334813512021Circ_0008305-mediated miR-660/BAG5 axis contributes to hepatocellular carcinoma tumorigenesis.10
341261572021Implication of BAG5 downregulation in metabolic reprogramming of cisplatin-resistant ovarian cancer cells via mTORC2 signaling pathway.3
325834302021Bcl-2-associated athanogene 5 overexpression attenuates catecholamine-induced vascular endothelial cell apoptosis.3
331866562021PRMT6 deficiency induces autophagy in hostile microenvironments of hepatocellular carcinoma tumors by regulating BAG5-associated HSC70 stability.12
334813512021Circ_0008305-mediated miR-660/BAG5 axis contributes to hepatocellular carcinoma tumorigenesis.10
341261572021Implication of BAG5 downregulation in metabolic reprogramming of cisplatin-resistant ovarian cancer cells via mTORC2 signaling pathway.3
319487582020miR-155 inhibits mitophagy through suppression of BAG5, a partner protein of PINK1.17
323500572020Signals from the Metastatic Niche Regulate Early and Advanced Ovarian Cancer Metastasis through miR-4454 Downregulation.10
330856442020Stress-induced p53 drives BAG5 cochaperone expression to control α-synuclein aggregation in Parkinson's disease.8
319487582020miR-155 inhibits mitophagy through suppression of BAG5, a partner protein of PINK1.17
323500572020Signals from the Metastatic Niche Regulate Early and Advanced Ovarian Cancer Metastasis through miR-4454 Downregulation.10

Citation

Dessen P

BAG5 (BAG cochaperone 5)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43161/bag5