BASP1 (brain abundant membrane attached signal protein 1)

2008-12-01  

Identity

HGNC
LOCATION
5p15.1
LOCUSID
ALIAS
CAP-23,CAP23,NAP-22,NAP22
FUSION GENES

Other Information

Locus ID:

NCBI: 10409
MIM: 605940
HGNC: 957
Ensembl: ENSG00000176788

Variants:

dbSNP: 10409
ClinVar: 10409
TCGA: ENSG00000176788
COSMIC: BASP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000176788ENST00000322611P80723
ENSG00000176788ENST00000606445U3KQP0
ENSG00000176788ENST00000616743P80723

Expression (GTEx)

0
100
200
300
400
500
600

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
182685002009Proteomic analysis of membrane microdomain-associated proteins in the dorsolateral prefrontal cortex in schizophrenia and bipolar disorder reveals alterations in LAMP, STXBP1 and BASP1 protein expression.55
147017282004BASP1 is a transcriptional cosuppressor for the Wilms' tumor suppressor protein WT1.46
229399832012Repression of transcription by WT1-BASP1 requires the myristoylation of BASP1 and the PIP2-dependent recruitment of histone deacetylase.28
212692712011WT1 and its transcriptional cofactor BASP1 redirect the differentiation pathway of an established blood cell line.19
282125422017Two-stage genome-wide association study identifies a novel susceptibility locus associated with melanoma.19
189493572008Identification of novel aberrant methylation of BASP1 and SRD5A2 for early diagnosis of hepatocellular carcinoma by genome-wide search.15
241664962014Prohibitin is required for transcriptional repression by the WT1-BASP1 complex.15
199568492010The assessment of methylated BASP1 and SRD5A2 levels in the detection of early hepatocellular carcinoma.6
284925432017BASP1 interacts with oestrogen receptor α and modifies the tamoxifen response.6
296746932018Methylation-associated silencing of BASP1 contributes to leukemogenesis in t(8;21) acute myeloid leukemia.6

Citation

Dessen P

BASP1 (brain abundant membrane attached signal protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2008-12-01

Online version: http://atlasgeneticsoncology.org/gene/50562/basp1