BCAS2 (BCAS2 pre-mRNA processing factor)

2003-02-01  

Identity

HGNC
LOCATION
1p13.2
LOCUSID
ALIAS
DAM1,SPF27,Snt309
FUSION GENES

Other Information

Locus ID:

NCBI: 10286
MIM: 605783
HGNC: 975
Ensembl: ENSG00000116752

Variants:

dbSNP: 10286
ClinVar: 10286
TCGA: ENSG00000116752
COSMIC: BCAS2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000116752ENST00000369541O75934
ENSG00000116752ENST00000369541B2R7W3

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Pathways

PathwaySourceExternal ID
SpliceosomeKEGGko03040
SpliceosomeKEGGhsa03040
Spliceosome, Prp19/CDC5L complexKEGGhsa_M00353
Spliceosome, 35S U5-snRNPKEGGhsa_M00355
Spliceosome, Prp19/CDC5L complexKEGGM00353
Spliceosome, 35S U5-snRNPKEGGM00355
Gene ExpressionREACTOMER-HSA-74160
Processing of Capped Intron-Containing Pre-mRNAREACTOMER-HSA-72203
mRNA SplicingREACTOMER-HSA-72172
mRNA Splicing - Major PathwayREACTOMER-HSA-72163

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
372484662023BCAS2 regulates granulosa cell survival by participating in mRNA alternative splicing.0
372484662023BCAS2 regulates granulosa cell survival by participating in mRNA alternative splicing.0
329633492020BCAS2, a protein enriched in advanced prostate cancer, interacts with NBS1 to enhance DNA double-strand break repair.4
329633492020BCAS2, a protein enriched in advanced prostate cancer, interacts with NBS1 to enhance DNA double-strand break repair.4
308133512019BCAS2 Enhances Carcinogenic Effects of Estrogen Receptor Alpha in Breast Cancer Cells.8
308133512019BCAS2 Enhances Carcinogenic Effects of Estrogen Receptor Alpha in Breast Cancer Cells.8
291155642018miR-486 functions as a tumor suppressor in esophageal cancer by targeting CDK4/BCAS2.22
291155642018miR-486 functions as a tumor suppressor in esophageal cancer by targeting CDK4/BCAS2.22
273562652016Novel IGH and MYC Translocation Partners in Diffuse Large B-Cell Lymphomas.5
273562652016Novel IGH and MYC Translocation Partners in Diffuse Large B-Cell Lymphomas.5
254618072015BCAS2 promotes prostate cancer cells proliferation by enhancing AR mRNA transcription and protein stability.12
263191522015BCAS2 interacts with HSF4 and negatively regulates its protein stability via ubiquitination.5
265606932015The molecular architecture of the Dam1 kinetochore complex is defined by cross-linking based structural modelling.32
254618072015BCAS2 promotes prostate cancer cells proliferation by enhancing AR mRNA transcription and protein stability.12
263191522015BCAS2 interacts with HSF4 and negatively regulates its protein stability via ubiquitination.5

Citation

Dessen P

BCAS2 (BCAS2 pre-mRNA processing factor)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/765/bcas2