Identity
HGNC
LOCATION
15q25.1
LOCUSID
ALIAS
ACC-1,ACC-2,ACC1,ACC2,BCL2L5,BFL1,GRS,HBPA1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 597
MIM: 601056
HGNC: 991
Ensembl: ENSG00000140379
Variants:
dbSNP: 597
ClinVar: 597
TCGA: ENSG00000140379
COSMIC: BCL2A1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000140379 | ENST00000267953 | Q16548 |
| ENSG00000140379 | ENST00000335661 | Q16548 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38059622 | 2024 | Epstein-Barr virus induces germinal center light zone chromatin architecture and promotes survival through enhancer looping at the BCL2A1 locus. | 1 |
| 38211832 | 2024 | MARCH5-mediated downregulation of ACC2 promotes fatty acid oxidation and tumor progression in ovarian cancer. | 0 |
| 38059622 | 2024 | Epstein-Barr virus induces germinal center light zone chromatin architecture and promotes survival through enhancer looping at the BCL2A1 locus. | 1 |
| 38211832 | 2024 | MARCH5-mediated downregulation of ACC2 promotes fatty acid oxidation and tumor progression in ovarian cancer. | 0 |
| 37415254 | 2023 | MiR-3976 regulates HCT-8 cell apoptosis and parasite burden by targeting BCL2A1 in response to Cryptosporidium parvum infection. | 1 |
| 37562004 | 2023 | CARD11 gain of function upregulates BCL2A1 expression and promotes resistance to targeted therapies combination in B-cell lymphoma. | 0 |
| 37889551 | 2023 | BCL2A1 is associated with tumor-associated macrophages and unfavorable prognosis in human gliomas. | 0 |
| 37415254 | 2023 | MiR-3976 regulates HCT-8 cell apoptosis and parasite burden by targeting BCL2A1 in response to Cryptosporidium parvum infection. | 1 |
| 37562004 | 2023 | CARD11 gain of function upregulates BCL2A1 expression and promotes resistance to targeted therapies combination in B-cell lymphoma. | 0 |
| 37889551 | 2023 | BCL2A1 is associated with tumor-associated macrophages and unfavorable prognosis in human gliomas. | 0 |
| 35603962 | 2022 | Construction of three-gene-based prognostic signature and analysis of immune cells infiltration in children and young adults with B-acute lymphoblastic leukemia. | 3 |
| 35832273 | 2022 | Bulk RNA Sequencing With Integrated Single-Cell RNA Sequencing Identifies BCL2A1 as a Potential Diagnostic and Prognostic Biomarker for Sepsis. | 1 |
| 35603962 | 2022 | Construction of three-gene-based prognostic signature and analysis of immune cells infiltration in children and young adults with B-acute lymphoblastic leukemia. | 3 |
| 35832273 | 2022 | Bulk RNA Sequencing With Integrated Single-Cell RNA Sequencing Identifies BCL2A1 as a Potential Diagnostic and Prognostic Biomarker for Sepsis. | 1 |
| 33391539 | 2021 | Molecular stratification by BCL2A1 and AIM2 provides additional prognostic value in penile squamous cell carcinoma. | 3 |
Citation
Dessen P
BCL2A1 (BCL2 related protein A1)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/770/bcl2a1
