Identity
HGNC
LOCATION
11q23.3
LOCUSID
ALIAS
B9L,BCL9-2,DLNB11
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 283149
MIM: 609004
HGNC: 23688
Ensembl: ENSG00000186174
Variants:
dbSNP: 283149
ClinVar: 283149
TCGA: ENSG00000186174
COSMIC: BCL9L
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000186174 | ENST00000334801 | Q86UU0 |
| ENSG00000186174 | ENST00000526143 | A0A087WZX0 |
| ENSG00000186174 | ENST00000532899 | E9PNR0 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35628130 | 2022 | Wnt/β-Catenin Signalling and Its Cofactor BCL9L Have an Oncogenic Effect in Bladder Cancer Cells. | 4 |
| 35628130 | 2022 | Wnt/β-Catenin Signalling and Its Cofactor BCL9L Have an Oncogenic Effect in Bladder Cancer Cells. | 4 |
| 33767438 | 2021 | BCL9/BCL9L promotes tumorigenicity through immune-dependent and independent mechanisms in triple negative breast cancer. | 15 |
| 34319913 | 2021 | Type I collagen promotes tumor progression of integrin β1 positive gastric cancer through a BCL9L/β-catenin signaling pathway. | 7 |
| 34545187 | 2021 | The interactions of Bcl9/Bcl9L with β-catenin and Pygopus promote breast cancer growth, invasion, and metastasis. | 12 |
| 33767438 | 2021 | BCL9/BCL9L promotes tumorigenicity through immune-dependent and independent mechanisms in triple negative breast cancer. | 15 |
| 34319913 | 2021 | Type I collagen promotes tumor progression of integrin β1 positive gastric cancer through a BCL9L/β-catenin signaling pathway. | 7 |
| 34545187 | 2021 | The interactions of Bcl9/Bcl9L with β-catenin and Pygopus promote breast cancer growth, invasion, and metastasis. | 12 |
| 30698996 | 2019 | miR-22 and miR-214 targeting BCL9L inhibit proliferation, metastasis, and epithelial-mesenchymal transition by down-regulating Wnt signaling in colon cancer. | 15 |
| 30698996 | 2019 | miR-22 and miR-214 targeting BCL9L inhibit proliferation, metastasis, and epithelial-mesenchymal transition by down-regulating Wnt signaling in colon cancer. | 15 |
| 28073006 | 2017 | BCL9L Dysfunction Impairs Caspase-2 Expression Permitting Aneuploidy Tolerance in Colorectal Cancer. | 55 |
| 28073006 | 2017 | BCL9L Dysfunction Impairs Caspase-2 Expression Permitting Aneuploidy Tolerance in Colorectal Cancer. | 55 |
| 27713160 | 2016 | Role of BCL9L in transforming growth factor-β (TGF-β)-induced epithelial-to-mesenchymal-transition (EMT) and metastasis of pancreatic cancer. | 16 |
| 27713160 | 2016 | Role of BCL9L in transforming growth factor-β (TGF-β)-induced epithelial-to-mesenchymal-transition (EMT) and metastasis of pancreatic cancer. | 16 |
| 25678599 | 2015 | The Tumor-Suppressor WWOX and HDAC3 Inhibit the Transcriptional Activity of the β-Catenin Coactivator BCL9-2 in Breast Cancer Cells. | 11 |
Citation
Dessen P
BCL9L (BCL9 like)
Atlas Genet Cytogenet Oncol Haematol. 2003-12-01
Online version: http://atlasgeneticsoncology.org/gene/782/bcl9l
