Identity
HGNC
LOCATION
17q21.31
LOCUSID
ALIAS
ATG6,VPS30,beclin1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8678
MIM: 604378
HGNC: 1034
Ensembl: ENSG00000126581
Variants:
dbSNP: 8678
ClinVar: 8678
TCGA: ENSG00000126581
COSMIC: BECN1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38177673 | 2024 | Reduction of DHHC5-mediated beclin 1 S-palmitoylation underlies autophagy decline in aging. | 0 |
| 38182563 | 2024 | GRB2 is a BECN1 interacting protein that regulates autophagy. | 1 |
| 38211653 | 2024 | Targeting IL-6/STAT3 signaling abrogates EGFR-TKI resistance through inhibiting Beclin-1 dependent autophagy in HNSCC. | 1 |
| 38360997 | 2024 | VHL suppresses autophagy and tumor growth through PHD1-dependent Beclin1 hydroxylation. | 1 |
| 38396816 | 2024 | THSD1 Suppresses Autophagy-Mediated Focal Adhesion Turnover by Modulating the FAK-Beclin 1 Pathway. | 0 |
| 38514065 | 2024 | Upregulation of miR-499a Targets Beclin1 to Modulate Astrocyte Autophagy and Promote Ischemic Stroke. | 0 |
| 38177673 | 2024 | Reduction of DHHC5-mediated beclin 1 S-palmitoylation underlies autophagy decline in aging. | 0 |
| 38182563 | 2024 | GRB2 is a BECN1 interacting protein that regulates autophagy. | 1 |
| 38211653 | 2024 | Targeting IL-6/STAT3 signaling abrogates EGFR-TKI resistance through inhibiting Beclin-1 dependent autophagy in HNSCC. | 1 |
| 38360997 | 2024 | VHL suppresses autophagy and tumor growth through PHD1-dependent Beclin1 hydroxylation. | 1 |
| 38396816 | 2024 | THSD1 Suppresses Autophagy-Mediated Focal Adhesion Turnover by Modulating the FAK-Beclin 1 Pathway. | 0 |
| 38514065 | 2024 | Upregulation of miR-499a Targets Beclin1 to Modulate Astrocyte Autophagy and Promote Ischemic Stroke. | 0 |
| 35699825 | 2023 | Upregulation of necroptosis markers RIPK3/MLKL and their crosstalk with autophagy-related protein Beclin-1 in primary immune thrombocytopenia. | 0 |
| 36586462 | 2023 | GAPR-1 Interferes with Condensate Formation of Beclin 1 in Saccharomyces cerevisiae. | 1 |
| 37040770 | 2023 | Beclin-1-dependent autophagy, but not apoptosis, is critical for stem-cell-mediated endometrial programming and the establishment of pregnancy. | 4 |
Citation
Dessen P
BECN1 (beclin 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/786/becn1
