BICC1 (BicC family RNA binding protein 1)

2014-11-01  

Identity

HGNC
BICC1
LOCATION
10q21.1
LOCUSID
80114
ALIAS
BICC,CYSRD
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 80114
MIM: 614295
HGNC: 19351
Ensembl: ENSG00000122870

Variants:

dbSNP: 80114
ClinVar: 80114
TCGA: ENSG00000122870
COSMIC: BICC1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000122870ENST00000263103A6NGY7
ENSG00000122870ENST00000373886Q9H694

Expression (GTEx)

0
10
20
30
40
50
60
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
205161562010Genome-wide association study of major recurrent depression in the U.K. population.87
163854512006A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.69
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
219225952012Two mutations in human BICC1 resulting in Wnt pathway hyperactivity associated with cystic renal dysplasia.27
247899092014Bicc1 is a genetic determinant of osteoblastogenesis and bone mineral density.23
247899092014Bicc1 is a genetic determinant of osteoblastogenesis and bone mineral density.23
229104602012Effect of genetic variant in BICC1 on functional and structural brain changes in depression.6
251784062015BICC1 expression is elevated in depressed subjects and contributes to depressive behavior in rodents.5
263914932016GWAS-identified risk variants for major depressive disorder: Preliminary support for an association with late-life depressive symptoms and brain structural alterations.5
284507402017The centrosomal OFD1 protein interacts with the translation machinery and regulates the synthesis of specific targets.5

Citation

Dessen P

BICC1 (BicC family RNA binding protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/60755/bicc1