Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 638
MIM: 603392
HGNC: 1051
Ensembl: ENSG00000100290
Variants:
dbSNP: 638
ClinVar: 638
TCGA: ENSG00000100290
COSMIC: BIK
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000100290 | ENST00000216115 | Q13323 |
| ENSG00000100290 | ENST00000216115 | A0A024R4X6 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Endocrine resistance | KEGG | ko01522 |
| Endocrine resistance | KEGG | hsa01522 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34962825 | 2022 | Rhomboid domain containing 1 promotes the growth of non-small cell lung cancer through the activation of EGFR and regulation of the BIK-mediated apoptosis. | 0 |
| 35008922 | 2022 | RNA Exosome Component EXOSC4 Amplified in Multiple Cancer Types Is Required for the Cancer Cell Survival. | 4 |
| 34962825 | 2022 | Rhomboid domain containing 1 promotes the growth of non-small cell lung cancer through the activation of EGFR and regulation of the BIK-mediated apoptosis. | 0 |
| 35008922 | 2022 | RNA Exosome Component EXOSC4 Amplified in Multiple Cancer Types Is Required for the Cancer Cell Survival. | 4 |
| 31635499 | 2020 | Correlation of the protein expression of GRP78 and BIK/NBK with prognostic markers in patients with breast cancer and neoadjuvant chemotherapy. | 4 |
| 31635499 | 2020 | Correlation of the protein expression of GRP78 and BIK/NBK with prognostic markers in patients with breast cancer and neoadjuvant chemotherapy. | 4 |
| 31387940 | 2019 | BIK ubiquitination by the E3 ligase Cul5-ASB11 determines cell fate during cellular stress. | 8 |
| 31460837 | 2019 | Upregulation of miR-1306-5p decreases cerebral ischemia/reperfusion injury in vitro by targeting BIK. | 0 |
| 31387940 | 2019 | BIK ubiquitination by the E3 ligase Cul5-ASB11 determines cell fate during cellular stress. | 8 |
| 31460837 | 2019 | Upregulation of miR-1306-5p decreases cerebral ischemia/reperfusion injury in vitro by targeting BIK. | 0 |
| 28412412 | 2017 | Autophagy regulatory molecule, TMEM74, interacts with BIK and inhibits BIK-induced apoptosis. | 8 |
| 28784260 | 2017 | Blocking Bcl-2 resolves IL-13-mediated mucous cell hyperplasia in a Bik-dependent manner. | 11 |
| 28796811 | 2017 | Biphasic ROS production, p53 and BIK dictate the mode of cell death in response to DNA damage in colon cancer cells. | 11 |
| 28412412 | 2017 | Autophagy regulatory molecule, TMEM74, interacts with BIK and inhibits BIK-induced apoptosis. | 8 |
| 28784260 | 2017 | Blocking Bcl-2 resolves IL-13-mediated mucous cell hyperplasia in a Bik-dependent manner. | 11 |
Citation
Dessen P
BIK (BCL2 interacting killer)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/793/bik
