BLID (BH3-like motif containing, cell death inducer)

2010-08-01 Affiliation

Identity

HGNC

BLID

LOCATION

11q24.1

LOCUSID

414899

ALIAS

BRCC2

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 414899
MIM: 608853
HGNC: 33495
Ensembl: ENSG00000259571

Variants:

dbSNP: 414899
ClinVar: 414899
TCGA: ENSG00000259571
COSMIC: BLID

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000259571	ENST00000560104	Q8IZY5

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

References

Pubmed ID	Year	Title	Citations
20544842	2010	MicroRNA-125b-1 and BLID upregulation resulting from a novel IGH translocation in childhood B-Cell precursor acute lymphoblastic leukemia.	12
20400521	2010	The proapoptotic molecule BLID interacts with Bcl-XL and its downregulation in breast cancer correlates with poor disease-free and overall survival.	6
15069058	2004	BRCC2, a novel BH3-like domain-containing protein, induces apoptosis in a caspase-dependent manner.	0
18940476	2008	Assignment of the BLID gene to 11q24.1 by fluorescence in situ hybridization.	0
19779542	2009	A genome-wide association analysis identified a novel susceptible locus for pathological myopia at 11q24.1.	0
21031016	2010	Evaluation of BLID and LOC399959 as candidate genes for high myopia in the Chinese Han population.	0
21846966	2011	Frequent loss of the BLID gene in early-onset breast cancer.	0
23928696	2013	BRCC2 inhibits breast cancer cell growth and metastasis in vitro and in vivo via downregulating AKT pathway.	0
24532431	2014	Aberrant BLID expression is associated with breast cancer progression.	0
25728273	2015	MicroRNA-575 targets BLID to promote growth and invasion of non-small cell lung cancer cells.	0

Citation

Dessen P

BLID (BH3-like motif containing, cell death inducer)

Atlas Genet Cytogenet Oncol Haematol. 2010-08-01

Online version: http://atlasgeneticsoncology.org/gene/51627/blid