Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 640
MIM: 191305
HGNC: 1057
Ensembl: ENSG00000136573
Variants:
dbSNP: 640
ClinVar: 640
TCGA: ENSG00000136573
COSMIC: BLK
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000136573 | ENST00000259089 | P51451 |
| ENSG00000136573 | ENST00000529894 | E9PJX5 |
| ENSG00000136573 | ENST00000645242 | E9PJX5 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36797256 | 2023 | B-lymphoid tyrosine kinase-mediated FAM83A phosphorylation elevates pancreatic tumorigenesis through interacting with β-catenin. | 11 |
| 36797256 | 2023 | B-lymphoid tyrosine kinase-mediated FAM83A phosphorylation elevates pancreatic tumorigenesis through interacting with β-catenin. | 11 |
| 35108381 | 2022 | Evaluation of Evidence for Pathogenicity Demonstrates That BLK, KLF11, and PAX4 Should Not Be Included in Diagnostic Testing for MODY. | 13 |
| 35108381 | 2022 | Evaluation of Evidence for Pathogenicity Demonstrates That BLK, KLF11, and PAX4 Should Not Be Included in Diagnostic Testing for MODY. | 13 |
| 33756160 | 2021 | BLK and BANK1 variants and interactions are associated with susceptibility for primary Sjögren's syndrome and with some clinical features. | 2 |
| 34637583 | 2021 | BLK polymorphisms and expression level in neuromyelitis optica spectrum disorder. | 5 |
| 33756160 | 2021 | BLK and BANK1 variants and interactions are associated with susceptibility for primary Sjögren's syndrome and with some clinical features. | 2 |
| 34637583 | 2021 | BLK polymorphisms and expression level in neuromyelitis optica spectrum disorder. | 5 |
| 32313195 | 2020 | Polymorphisms of BLK are associated with renal disorder in patients with systemic lupus erythematosus. | 1 |
| 32313195 | 2020 | Polymorphisms of BLK are associated with renal disorder in patients with systemic lupus erythematosus. | 1 |
| 30589937 | 2019 | Associations of secreted phosphoprotein 1 and B lymphocyte kinase gene polymorphisms with autoimmune thyroid disease. | 3 |
| 31101814 | 2019 | Functional rare and low frequency variants in BLK and BANK1 contribute to human lupus. | 40 |
| 31134304 | 2019 | BLK and BANK1 polymorphisms and interactions are associated in Mexican patients with systemic lupus erythematosus. | 5 |
| 30589937 | 2019 | Associations of secreted phosphoprotein 1 and B lymphocyte kinase gene polymorphisms with autoimmune thyroid disease. | 3 |
| 31101814 | 2019 | Functional rare and low frequency variants in BLK and BANK1 contribute to human lupus. | 40 |
Citation
Dessen P
BLK (BLK proto-oncogene, Src family tyrosine kinase)
Atlas Genet Cytogenet Oncol Haematol. 2003-08-01
Online version: http://atlasgeneticsoncology.org/gene/802/blk
