Atlas of Genetics and Cytogenetics in Oncology and Haematology

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BMP10 (bone morphogenetic protein 10)

Identity

Other names-
HGNC (Hugo) BMP10
LocusID (NCBI) 27302
Location 2p13.3
Location_base_pair Starts at 69092613 and ends at 69098649 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)BMP10   20869
Entrez_Gene (NCBI)BMP10  27302  bone morphogenetic protein 10
Cards
GeneCards (Weizmann)BMP10
Ensembl (Hinxton)ENSG00000163217 [Gene_View]  chr2:69092613-69098649 [Contig_View]  BMP10 [Vega]
AceView (NCBI)BMP10
Genatlas (Paris)BMP10
SOURCE (Stanford)NM_014482
Genomic and cartography
GoldenPath (UCSC)BMP10  -  2p13.3   chr2:69092613-69098649 -  2p13.3   [Description]    (hg19-Feb_2009)
EnsemblBMP10 - 2p13.3 [CytoView]
Mapping of homologs : NCBIBMP10 [Mapview]
OMIM608748   
Gene and transcription
Genbank (Entrez)AF101441 BC069080 BC101734 BC105063
RefSeq transcript (SRS)NM_014482
RefSeq transcript (Entrez)NM_014482
RefSeq genomic (SRS)AC_000134 NC_000002 NC_018913 NG_032117 NT_022184 NW_001838769 NW_004078005
RefSeq genomic (Entrez)AC_000134 NC_000002 NC_018913 NG_032117 NT_022184 NW_001838769 NW_004078005
Consensus coding sequences : CCDS (NCBI)BMP10
Cluster EST : UnigeneHs.158317 [ SRS ] Hs.158317 [ NCBI ]
CGAP (NCI)Hs.158317
Alternative Splicing : Fast-db (Paris)GSHG0017694
Alternative Splicing GalleryENSG00000163217
Gene ExpressionBMP10 [ NCBI-GEO ]   BMP10 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95393 (SRS) O95393 (Uniprot)
NextProtO95393
With graphics : InterProO95393
Splice isoforms : SwissVarO95393(Swissvar)
Domaine pattern : Prosite (SRS)TGF_BETA_1 (PS00250)    TGF_BETA_2 (PS51362)   
Domaine pattern : Prosite (Expaxy)TGF_BETA_1 (PS00250)    TGF_BETA_2 (PS51362)   
Domains : Interpro (SRS)Inhibin_asu    TGF-b_C    TGF-b_N    TGF-beta-rel    TGFb_CS   
Domains : Interpro (EBI)Inhibin_asu    TGF-b_C    TGF-b_N    TGF-beta-rel    TGFb_CS   
Related proteins : CluSTrO95393
Domain families : Pfam (SRS)TGF_beta (PF00019)    TGFb_propeptide (PF00688)   
Domain families : Pfam (Sanger)TGF_beta (PF00019)    TGFb_propeptide (PF00688)   
Domain families : Pfam (NCBI)pfam00019    pfam00688   
Domain families : Smart (EMBL)TGFB (SM00204)  
DMDM27302
Blocks (Seattle)O95393
Human Protein AtlasENSG00000163217
HPRD09788
IPIIPI00030115   
Protein Interaction databases
DIP (DOE-UCLA)O95393
IntAct (EBI)O95393
FunCoupENSG00000163217
REACTOMEBMP10
Protein Interaction Database27302
BioGRIDBMP10
InParanoidO95393
Interologous Interaction database O95393
IntegromeDBBMP10
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)BMP10
SNP (GeneSNP Utah)BMP10
SNP : HGBaseBMP10
Genetic variants : HAPMAPBMP10
Somatic Mutations in Cancer : COSMICBMP10 
CONAN: Copy Number AnalysisBMP10 
Mutations and Diseases : HGMDBMP10
OMIM608748   
GENETests608748   
Disease Genetic AssociationBMP10
Huge Navigator BMP10 [HugePedia]  BMP10 [HugeCancerGEM]
Genomic VariantsBMP10  BMP10 [DGVbeta]
snp3D : Map Gene to Disease27302
General knowledge
Homologs : HomoloGeneBMP10
Homology/Alignments : Family Browser (UCSC)BMP10
Phylogenetic Trees/Animal Genes : TreeFamBMP10
Chemical/Protein Interactions : CTD27302
Chemical/Pharm GKB GenePA134953092
Clinical trialBMP10
Cancer Resource (Charite)ENSG00000163217
Ontology : AmiGOcytokine activity  hormone activity  protein binding  extracellular space  cytoplasm  Notch signaling pathway  adult heart development  growth factor activity  cell surface  negative regulation of endothelial cell migration  positive regulation of cardiac muscle hypertrophy  negative regulation of cardiac muscle hypertrophy  positive regulation of pathway-restricted SMAD protein phosphorylation  cardiac muscle hypertrophy in response to stress  Z disc  negative regulation of cell growth  negative regulation of cell migration  BMP signaling pathway  activin receptor signaling pathway  receptor serine/threonine kinase binding  sarcomere organization  positive regulation of transcription, DNA-dependent  atrial cardiac muscle tissue morphogenesis  ventricular cardiac muscle tissue morphogenesis  ventricular cardiac muscle cell development  regulation of cardiac muscle contraction  cardiac muscle cell proliferation  positive regulation of cardiac muscle cell proliferation  positive regulation of sarcomere organization  heart trabecula formation  pathway-restricted SMAD protein phosphorylation  positive regulation of cell proliferation involved in heart morphogenesis  
Ontology : EGO-EBIcytokine activity  hormone activity  protein binding  extracellular space  cytoplasm  Notch signaling pathway  adult heart development  growth factor activity  cell surface  negative regulation of endothelial cell migration  positive regulation of cardiac muscle hypertrophy  negative regulation of cardiac muscle hypertrophy  positive regulation of pathway-restricted SMAD protein phosphorylation  cardiac muscle hypertrophy in response to stress  Z disc  negative regulation of cell growth  negative regulation of cell migration  BMP signaling pathway  activin receptor signaling pathway  receptor serine/threonine kinase binding  sarcomere organization  positive regulation of transcription, DNA-dependent  atrial cardiac muscle tissue morphogenesis  ventricular cardiac muscle tissue morphogenesis  ventricular cardiac muscle cell development  regulation of cardiac muscle contraction  cardiac muscle cell proliferation  positive regulation of cardiac muscle cell proliferation  positive regulation of sarcomere organization  heart trabecula formation  pathway-restricted SMAD protein phosphorylation  positive regulation of cell proliferation involved in heart morphogenesis  
Pathways : BIOCARTAALK in cardiac myocytes [Genes]   
Other databases
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
PubGeneBMP10
iHOPBMP10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:30:41 CEST 2013
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