BMP3 (bone morphogenetic protein 3)

2003-12-01 Affiliation

Identity

HGNC

BMP3

LOCATION

4q21.21

LOCUSID

651

ALIAS

BMP-3A

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 651
MIM: 112263
HGNC: 1070
Ensembl: ENSG00000152785

Variants:

dbSNP: 651
ClinVar: 651
TCGA: ENSG00000152785
COSMIC: BMP3

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000152785	ENST00000282701	P12645

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

References

Pubmed ID	Year	Title	Citations
20734064	2010	A large-scale candidate gene association study of age at menarche and age at natural menopause.	38
17924656	2007	BMP-3 and BMP-6 structures illuminate the nature of binding specificity with receptors.	34
18311777	2008	Bone morphogenic protein 3 inactivation is an early and frequent event in colorectal cancer development.	32
20143330	2010	BMP-3 promotes mesenchymal stem cell proliferation through the TGF-beta/activin signaling pathway.	28
19453261	2009	High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men.	20
21415150	2011	Circulating bone morphogenetic protein 1-3 isoform increases renal fibrosis.	15
29892846	2018	BMP3 promoter hypermethylation in plasma-derived cell-free DNA in colorectal cancer patients.	10
20238409	2010	Role of BMP3 in progression of gastric carcinoma in Chinese people.	8
29649414	2018	miR-450b Promotes Osteogenic Differentiation In Vitro and Enhances Bone Formation In Vivo by Targeting BMP3.	6
22303795	2011	8.6Mb interstitial deletion of chromosome 4q13.3q21.23 in a boy with cognitive impairment, short stature, hearing loss, skeletal abnormalities and facial dysmorphism.	5

Citation

Dessen P

BMP3 (bone morphogenetic protein 3)

Atlas Genet Cytogenet Oncol Haematol. 2003-12-01

Online version: http://atlasgeneticsoncology.org/gene/810/bmp3