Identity
HGNC
LOCATION
2q33.1
LOCUSID
ALIAS
BMPR-II,BMPR3,BMR2,BRK-3,POVD1,PPH1,T-ALK
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 659
MIM: 600799
HGNC: 1078
Ensembl: ENSG00000204217
Variants:
dbSNP: 659
ClinVar: 659
TCGA: ENSG00000204217
COSMIC: BMPR2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000204217 | ENST00000374574 | Q13873 |
| ENSG00000204217 | ENST00000374580 | Q13873 |
| ENSG00000204217 | ENST00000638587 | A0A1W2PPB5 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38473983 | 2024 | Hemodynamic and Clinical Profiles of Pulmonary Arterial Hypertension Patients with GDF2 and BMPR2 Variants. | 0 |
| 38717032 | 2024 | MiR-143-3p regulates chondrogenic differentiation of synovium derived mesenchymal stem cells under mechanical stress through the BMPR2-Smad signalling pathway by targeting BMPR2. | 0 |
| 38791441 | 2024 | BMPR2 Loss Activates AKT by Disrupting DLL4/NOTCH1 and PPARγ Signaling in Pulmonary Arterial Hypertension. | 0 |
| 38473983 | 2024 | Hemodynamic and Clinical Profiles of Pulmonary Arterial Hypertension Patients with GDF2 and BMPR2 Variants. | 0 |
| 38717032 | 2024 | MiR-143-3p regulates chondrogenic differentiation of synovium derived mesenchymal stem cells under mechanical stress through the BMPR2-Smad signalling pathway by targeting BMPR2. | 0 |
| 38791441 | 2024 | BMPR2 Loss Activates AKT by Disrupting DLL4/NOTCH1 and PPARγ Signaling in Pulmonary Arterial Hypertension. | 0 |
| 36672250 | 2023 | PTPN1 Deficiency Modulates BMPR2 Signaling and Induces Endothelial Dysfunction in Pulmonary Arterial Hypertension. | 2 |
| 36675162 | 2023 | BMPR2 Variants Underlie Nonsyndromic Oligodontia. | 0 |
| 36744494 | 2023 | Dysregulated Smooth Muscle Cell BMPR2-ARRB2 Axis Causes Pulmonary Hypertension. | 8 |
| 36907526 | 2023 | BMPR2 as a Novel Predisposition Gene for Hereditary Colorectal Polyposis. | 2 |
| 36917778 | 2023 | Vascular-Parenchymal Cross-Talk Promotes Lung Fibrosis through BMPR2 Signaling. | 14 |
| 37094738 | 2023 | Isolated Pulmonary Arteriovenous Malformations Associated With BMPR2 Pathogenic Variants. | 1 |
| 37191488 | 2023 | Imaging Features in BMPR2 Mutation-associated Pulmonary Arterial Hypertension. | 0 |
| 37278169 | 2023 | [Hereditary pulmonary hypertension family with BMPR2 gene variation: a case report and literature review]. | 0 |
| 37558836 | 2023 | Human liver single nuclear RNA sequencing implicates BMPR2, GDF15, arginine, and estrogen in portopulmonary hypertension. | 0 |
Citation
Dessen P
BMPR2 (bone morphogenetic protein receptor type 2)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/818/bmpr2
