BSG (basigin (Ok blood group))

2003-06-01  

Identity

HGNC
LOCATION
19p13.3
LOCUSID
ALIAS
5F7,CD147,EMMPRIN,EMPRIN,HAb18G,OK,SLC7A11,TCSF
FUSION GENES

Other Information

Locus ID:

NCBI: 682
MIM: 109480
HGNC: 1116
Ensembl: ENSG00000172270

Variants:

dbSNP: 682
ClinVar: 682
TCGA: ENSG00000172270
COSMIC: BSG

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000172270ENST00000333511P35613
ENSG00000172270ENST00000346916P35613
ENSG00000172270ENST00000353555P35613
ENSG00000172270ENST00000353555Q54A51
ENSG00000172270ENST00000545507P35613
ENSG00000172270ENST00000573216I3L192
ENSG00000172270ENST00000573784R4GMX5
ENSG00000172270ENST00000576984R4GN83
ENSG00000172270ENST00000613627A0A087X2B5
ENSG00000172270ENST00000614867A0A087X215
ENSG00000172270ENST00000618006A0A087WUV8
ENSG00000172270ENST00000618112A0A2R8YDZ0

Expression (GTEx)

0
100
200
300
400
500
600
700
800
900

Pathways

PathwaySourceExternal ID
HemostasisREACTOMER-HSA-109582
Cell surface interactions at the vascular wallREACTOMER-HSA-202733
Basigin interactionsREACTOMER-HSA-210991
Transmembrane transport of small moleculesREACTOMER-HSA-382551
SLC-mediated transmembrane transportREACTOMER-HSA-425407
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compoundsREACTOMER-HSA-425366
Proton-coupled monocarboxylate transportREACTOMER-HSA-433692
MetabolismREACTOMER-HSA-1430728
The citric acid (TCA) cycle and respiratory electron transportREACTOMER-HSA-1428517
Pyruvate metabolism and Citric Acid (TCA) cycleREACTOMER-HSA-71406
Pyruvate metabolismREACTOMER-HSA-70268
Extracellular matrix organizationREACTOMER-HSA-1474244
Degradation of the extracellular matrixREACTOMER-HSA-1474228
Integrin cell surface interactionsREACTOMER-HSA-216083

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
220809522011Basigin is a receptor essential for erythrocyte invasion by Plasmodium falciparum.222
158338502005Extracellular matrix metalloproteinase inducer stimulates tumor angiogenesis by elevating vascular endothelial cell growth factor and matrix metalloproteinases.97
119437752002Active site residues of cyclophilin A are crucial for its signaling activity via CD147.95
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
251325482014Structure of malaria invasion protein RH5 with erythrocyte basigin and blocking antibodies.80
127929082003Basigin (CD147): a multifunctional transmembrane protein involved in reproduction, neural function, inflammation and tumor invasion.79
157117332005Roles of the multifunctional glycoprotein, emmprin (basigin; CD147), in tumour progression.78
174607792007Tumor vesicle-associated CD147 modulates the angiogenic capability of endothelial cells.78
232588462013Monocarboxylate transporters (MCTs) in gliomas: expression and exploitation as therapeutic targets.78
152013412004Links between CD147 function, glycosylation, and caveolin-1.75

Citation

Dessen P

BSG (basigin (Ok blood group))

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/845/bsg