Identity
HGNC
LOCATION
19p13.11
LOCUSID
ALIAS
CD317,HM1.24,TETHERIN
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 684
MIM: 600534
HGNC: 1119
Ensembl: ENSG00000130303
Variants:
dbSNP: 684
ClinVar: 684
TCGA: ENSG00000130303
COSMIC: BST2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000130303 | ENST00000252593 | Q10589 |
| ENSG00000130303 | ENST00000252593 | A0A024R7H5 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38197534 | 2024 | BST2 promotes gastric cancer metastasis under the regulation of HOXD9 and PABPC1. | 0 |
| 38360199 | 2024 | Neuronal BST2: A Pruritic Mediator alongside Protease-Activated Receptor 2 in the IL-27-Driven Itch Pathway. | 0 |
| 38747016 | 2024 | Autophagy-related protein 5 (ATG5) interacts with bone marrow stromal cell antigen 2 (BST2) to stimulate HBV replication through antagonizing the antiviral activity of BST2. | 0 |
| 38197534 | 2024 | BST2 promotes gastric cancer metastasis under the regulation of HOXD9 and PABPC1. | 0 |
| 38360199 | 2024 | Neuronal BST2: A Pruritic Mediator alongside Protease-Activated Receptor 2 in the IL-27-Driven Itch Pathway. | 0 |
| 38747016 | 2024 | Autophagy-related protein 5 (ATG5) interacts with bone marrow stromal cell antigen 2 (BST2) to stimulate HBV replication through antagonizing the antiviral activity of BST2. | 0 |
| 36594082 | 2023 | BST2 induced macrophage M2 polarization to promote the progression of colorectal cancer. | 0 |
| 36602368 | 2023 | Interleukin-27 Promotes Divergent Effects on HIV-1 Infection in Peripheral Blood Mononuclear Cells through BST-2/Tetherin. | 1 |
| 36929425 | 2023 | BST2 regulated by the transcription factor STAT1 can promote metastasis, invasion and proliferation of oral squamous cell carcinoma via the AKT/ERK1/2 signaling pathway. | 3 |
| 37155854 | 2023 | ATG5 selectively engages virus-tethered BST2/tetherin in an LC3C-associated pathway. | 2 |
| 37210387 | 2023 | CD317 maintains proteostasis and cell survival in response to proteasome inhibitors by targeting calnexin for RACK1-mediated autophagic degradation. | 1 |
| 37211321 | 2023 | Understanding how transmembrane domains regulate interactions between human BST-2 and the SARS-CoV-2 accessory protein ORF7a. | 2 |
| 37818801 | 2023 | Tetherin antagonism by SARS-CoV-2 ORF3a and spike protein enhances virus release. | 8 |
| 37922253 | 2023 | Human BST2 inhibits rabies virus release independently of cysteine-linked dimerization and asparagine-linked glycosylation. | 1 |
| 38140605 | 2023 | Tetherin Restricts SARS-CoV-2 despite the Presence of Multiple Viral Antagonists. | 2 |
Citation
Dessen P
BST2 (bone marrow stromal cell antigen 2)
Atlas Genet Cytogenet Oncol Haematol. 2009-01-01
Online version: http://atlasgeneticsoncology.org/gene/50634/bst2
