Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 685
MIM: 600345
HGNC: 1121
Ensembl: ENSG00000174808
Variants:
dbSNP: 685
ClinVar: 685
TCGA: ENSG00000174808
COSMIC: BTC
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000174808 | ENST00000395743 | P35070 |
| ENSG00000174808 | ENST00000395743 | A0A0S2Z437 |
| ENSG00000174808 | ENST00000512743 | H0Y8Q5 |
Expression (GTEx)
Pathways
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA10040 | cetuximab | Chemical | Pathway | associated | |||
| PA162373091 | panitumumab | Chemical | Pathway | associated |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37231448 | 2023 | Betacellulin regulates gap junction intercellular communication by inducing the phosphorylation of connexin 43 in human granulosa-lutein cells. | 1 |
| 37231448 | 2023 | Betacellulin regulates gap junction intercellular communication by inducing the phosphorylation of connexin 43 in human granulosa-lutein cells. | 1 |
| 31654720 | 2020 | Betacellulin enhances ovarian cancer cell migration by up-regulating Connexin43 via MEK-ERK signaling. | 8 |
| 31654720 | 2020 | Betacellulin enhances ovarian cancer cell migration by up-regulating Connexin43 via MEK-ERK signaling. | 8 |
| 30249613 | 2018 | Betacellulin (BTC) Biases the EGFR To Dimerize with ErbB3. | 13 |
| 30249613 | 2018 | Betacellulin (BTC) Biases the EGFR To Dimerize with ErbB3. | 13 |
| 27129169 | 2016 | Betacellulin induces Slug-mediated down-regulation of E-cadherin and cell migration in ovarian cancer cells. | 12 |
| 27129169 | 2016 | Betacellulin induces Slug-mediated down-regulation of E-cadherin and cell migration in ovarian cancer cells. | 12 |
| 24629040 | 2014 | Regulatory mechanisms of betacellulin in CXCL8 production from lung cancer cells. | 10 |
| 24629040 | 2014 | Regulatory mechanisms of betacellulin in CXCL8 production from lung cancer cells. | 10 |
| 24092824 | 2013 | EGF-like growth factors induce COX-2-derived PGE2 production through ERK1/2 in human granulosa cells. | 20 |
| 24092824 | 2013 | EGF-like growth factors induce COX-2-derived PGE2 production through ERK1/2 in human granulosa cells. | 20 |
| 22183345 | 2012 | Regulation of retinal vascular permeability by betacellulin. | 1 |
| 22183345 | 2012 | Regulation of retinal vascular permeability by betacellulin. | 1 |
| 20165885 | 2010 | Betacellulin inhibits osteogenic differentiation and stimulates proliferation through HIF-1alpha. | 11 |
Citation
Dessen P
BTC (betacellulin)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45533/btc
