Identity
HGNC
LOCATION
5q13.2
LOCUSID
ALIAS
BETA-NAC,BTF3a,BTF3b,NACB
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 689
MIM: 602542
HGNC: 1125
Ensembl: ENSG00000145741
Variants:
dbSNP: 689
ClinVar: 689
TCGA: ENSG00000145741
COSMIC: BTF3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000145741 | ENST00000335895 | P20290 |
| ENSG00000145741 | ENST00000380591 | P20290 |
| ENSG00000145741 | ENST00000507081 | D6RDG3 |
| ENSG00000145741 | ENST00000509708 | H0Y9Y1 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38340226 | 2024 | Ubiquitination-specific protease 7 enhances stemness of hepatocellular carcinoma by stabilizing basic transcription factor 3. | 0 |
| 38340226 | 2024 | Ubiquitination-specific protease 7 enhances stemness of hepatocellular carcinoma by stabilizing basic transcription factor 3. | 0 |
| 37382415 | 2023 | BTF3 promotes proliferation and glycolysis in hepatocellular carcinoma by regulating GLUT1. | 3 |
| 37382415 | 2023 | BTF3 promotes proliferation and glycolysis in hepatocellular carcinoma by regulating GLUT1. | 3 |
| 33383560 | 2021 | BTF3 promotes stemness and inhibits TypeⅠInterferon signaling pathway in triple-negative breast cancer. | 3 |
| 33414468 | 2021 | BTF3 confers oncogenic activity in prostate cancer through transcriptional upregulation of Replication Factor C. | 6 |
| 34293363 | 2021 | BTF3-mediated regulation of BMI1 promotes colorectal cancer through influencing epithelial-mesenchymal transition and stem cell-like traits. | 8 |
| 33383560 | 2021 | BTF3 promotes stemness and inhibits TypeⅠInterferon signaling pathway in triple-negative breast cancer. | 3 |
| 33414468 | 2021 | BTF3 confers oncogenic activity in prostate cancer through transcriptional upregulation of Replication Factor C. | 6 |
| 34293363 | 2021 | BTF3-mediated regulation of BMI1 promotes colorectal cancer through influencing epithelial-mesenchymal transition and stem cell-like traits. | 8 |
| 32582971 | 2020 | miR‑802 inhibits the epithelial‑mesenchymal transition, migration and invasion of cervical cancer by regulating BTF3. | 4 |
| 32582971 | 2020 | miR‑802 inhibits the epithelial‑mesenchymal transition, migration and invasion of cervical cancer by regulating BTF3. | 4 |
| 30315845 | 2019 | Inhibition of BTF3 sensitizes luminal breast cancer cells to PI3Kα inhibition through the transcriptional regulation of ERα. | 15 |
| 31138311 | 2019 | BTF3 sustains cancer stem-like phenotype of prostate cancer via stabilization of BMI1. | 18 |
| 31263147 | 2019 | Positive expression of basic transcription factor 3 predicts poor survival of colorectal cancer patients: possible mechanisms involved. | 4 |
Citation
Dessen P
BTF3 (basic transcription factor 3)
Atlas Genet Cytogenet Oncol Haematol. 2007-10-01
Online version: http://atlasgeneticsoncology.org/gene/49761/btf3
