Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 151888
MIM: 607925
HGNC: 21087
Ensembl: ENSG00000186265
Variants:
dbSNP: 151888
ClinVar: 151888
TCGA: ENSG00000186265
COSMIC: BTLA
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000186265 | ENST00000334529 | Q7Z6A9 |
| ENSG00000186265 | ENST00000383680 | Q7Z6A9 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Immune System | REACTOME | R-HSA-168256 |
| Adaptive Immune System | REACTOME | R-HSA-1280218 |
| Costimulation by the CD28 family | REACTOME | R-HSA-388841 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38418488 | 2024 | BTLA contributes to acute-on-chronic liver failure infection and mortality through CD4(+) T-cell exhaustion. | 0 |
| 38928307 | 2024 | The Immune Checkpoint BTLA in Oral Cancer: Expression Analysis and Its Correlation to Other Immune Modulators. | 0 |
| 38418488 | 2024 | BTLA contributes to acute-on-chronic liver failure infection and mortality through CD4(+) T-cell exhaustion. | 0 |
| 38928307 | 2024 | The Immune Checkpoint BTLA in Oral Cancer: Expression Analysis and Its Correlation to Other Immune Modulators. | 0 |
| 37041226 | 2023 | BTLA dysregulation correlates with poor outcome and diminished T cell-mediated antitumor responses in chronic lymphocytic leukemia. | 4 |
| 37655751 | 2023 | B- and T-lymphocyte attenuator could be a new player in accelerated atherosclerosis associated with chronic kidney disease. | 0 |
| 37041226 | 2023 | BTLA dysregulation correlates with poor outcome and diminished T cell-mediated antitumor responses in chronic lymphocytic leukemia. | 4 |
| 37655751 | 2023 | B- and T-lymphocyte attenuator could be a new player in accelerated atherosclerosis associated with chronic kidney disease. | 0 |
| 35196150 | 2022 | Clinical Significance of BTLA and HVEM Expression on Circulating CD4(+) T and CD8(+) T Cells in Chronic Hepatitis B Virus Infection. | 4 |
| 35537322 | 2022 | The role of the BTLA-HVEM complex in the pathogenesis of autoimmune diseases. | 10 |
| 35945755 | 2022 | The correlation of BTLA rs1982809 polymorphism with cancer susceptibility: A meta-analysis of 8634 participators. | 0 |
| 35958579 | 2022 | Early detection of soluble CD27, BTLA, and TIM-3 predicts the development of nosocomial infection in pediatric burn patients. | 4 |
| 36081508 | 2022 | BTLA inhibition has a dominant role in the cis-complex of BTLA and HVEM. | 10 |
| 36552785 | 2022 | Tumor Cell-Intrinsic BTLA Receptor Inhibits the Proliferation of Tumor Cells via ERK1/2. | 6 |
| 36741370 | 2022 | The association of BTLA gene polymorphisms with non-small lung cancer risk in smokers and never-smokers. | 5 |
Citation
Dessen P
BTLA (B and T lymphocyte associated)
Atlas Genet Cytogenet Oncol Haematol. 2010-04-01
Online version: http://atlasgeneticsoncology.org/gene/51441/btla
