C10orf90 (chromosome 10 open reading frame 90)

2012-05-01  

Identity

HGNC
LOCATION
10q26.2
LOCUSID
ALIAS
FATS,bA422P15.2
FUSION GENES

Other Information

Locus ID:

NCBI: 118611
MIM: 617735
HGNC: 26563
Ensembl: ENSG00000154493

Variants:

dbSNP: 118611
ClinVar: 118611
TCGA: ENSG00000154493
COSMIC: C10orf90

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000154493ENST00000284694Q96M02
ENSG00000154493ENST00000356858Q5T025
ENSG00000154493ENST00000424927H7C3F8
ENSG00000154493ENST00000432642A0A0A0MSX2
ENSG00000154493ENST00000463082S4R3Q7
ENSG00000154493ENST00000480379A0A0C4DGS3
ENSG00000154493ENST00000488181S4R3N7

Expression (GTEx)

0
5
10
15

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
208440832010Centriolar association of ALMS1 and likely centrosomal functions of the ALMS motif-containing proteins C10orf90 and KIAA1731.35
242406852014FATS is an E2-independent ubiquitin ligase that stabilizes p53 and promotes its activation in response to DNA damage.8
220404992011Expression level of novel tumor suppressor gene FATS is associated with the outcome of node positive breast cancer.2
262233542015A functional genetic variant in fragile-site gene FATS modulates the risk of breast cancer in triparous women.1
284022752017The value of FATS expression in predicting sensitivity to radiotherapy in breast cancer.0
317708492019[Expression of FATS in non-small cell lung cancer and its relationship with prognosis].0

Citation

Dessen P

C10orf90 (chromosome 10 open reading frame 90)

Atlas Genet Cytogenet Oncol Haematol. 2012-05-01

Online version: http://atlasgeneticsoncology.org/gene/52693/c10orf90