C1RL (complement C1r subcomponent like)

2014-11-01  

Identity

HGNC
C1RL
LOCATION
12p13.31
LOCUSID
51279
ALIAS
C1RL1,C1RLP,C1r-LP,CLSPa
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 51279
MIM: 608974
HGNC: 21265
Ensembl: ENSG00000139178

Variants:

dbSNP: 51279
ClinVar: 51279
TCGA: ENSG00000139178
COSMIC: C1RL

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000139178ENST00000266542Q9NZP8
ENSG00000139178ENST00000534950H0YFL7
ENSG00000139178ENST00000534969H0YF87
ENSG00000139178ENST00000537833H0YFJ9
ENSG00000139178ENST00000539803H0YGP8
ENSG00000139178ENST00000543933F5H6S5
ENSG00000139178ENST00000544702F5GWF3
ENSG00000139178ENST00000545280F5H2Z5
ENSG00000139178ENST00000545337F5H7C8

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
194235402009Common variation in genes related to innate immunity and risk of adult glioma.19
153856752004Prohaptoglobin is proteolytically cleaved in the endoplasmic reticulum by the complement C1r-like protein.17
204069642010Risk of meningioma and common variation in genes related to innate immunity.12
193444142009Risk of non-Hodgkin lymphoma in association with germline variation in complement genes.8
204387852010Polymorphisms in innate immunity genes and risk of childhood leukemia.5
153581802004A novel human dendritic cell-derived C1r-like serine protease analog inhibits complement-mediated cytotoxicity.2

Citation

Dessen P

C1RL (complement C1r subcomponent like)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/61104/c1rl