Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 720
MIM: 120810
HGNC: 1323
Ensembl: ENSG00000244731
Variants:
dbSNP: 720
ClinVar: 720
TCGA: ENSG00000244731
COSMIC: C4A
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000244731 | ENST00000428956 | P0C0L4 |
| ENSG00000244731 | ENST00000498271 | P0C0L4 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35017157 | 2023 | Serum complement component 3, complement component 4 and complement component 1q levels predict progressive visual field loss in older women with primary angle closure glaucoma. | 4 |
| 36882872 | 2023 | Multi-ancestry phenome-wide association of complement component 4 variation with psychiatric and brain phenotypes in youth. | 3 |
| 35017157 | 2023 | Serum complement component 3, complement component 4 and complement component 1q levels predict progressive visual field loss in older women with primary angle closure glaucoma. | 4 |
| 36882872 | 2023 | Multi-ancestry phenome-wide association of complement component 4 variation with psychiatric and brain phenotypes in youth. | 3 |
| 34358307 | 2022 | The BS variant of C4 protects against age-related loss of white matter microstructural integrity. | 0 |
| 35142023 | 2022 | Protein phosphatase 2A and complement component 4 are linked to the protective effect of APOE ɛ2 for Alzheimer's disease. | 12 |
| 35315244 | 2022 | Complement C4 Copy Number Variation is Linked to SSA/Ro and SSB/La Autoantibodies in Systemic Inflammatory Autoimmune Diseases. | 10 |
| 35898513 | 2022 | Plasma Complement 3 and Complement 4 Are Promising Biomarkers for Distinguishing NMOSD From MOGAD and Are Associated With the Blood-Brain-Barrier Disruption in NMOSD. | 0 |
| 35995342 | 2022 | Association of complement component 4 with neuroimmune abnormalities in the subventricular zone in schizophrenia and autism spectrum disorders. | 4 |
| 36329007 | 2022 | Cerebrospinal fluid concentration of complement component 4A is increased in first episode schizophrenia. | 5 |
| 34358307 | 2022 | The BS variant of C4 protects against age-related loss of white matter microstructural integrity. | 0 |
| 35142023 | 2022 | Protein phosphatase 2A and complement component 4 are linked to the protective effect of APOE ɛ2 for Alzheimer's disease. | 12 |
| 35315244 | 2022 | Complement C4 Copy Number Variation is Linked to SSA/Ro and SSB/La Autoantibodies in Systemic Inflammatory Autoimmune Diseases. | 10 |
| 35898513 | 2022 | Plasma Complement 3 and Complement 4 Are Promising Biomarkers for Distinguishing NMOSD From MOGAD and Are Associated With the Blood-Brain-Barrier Disruption in NMOSD. | 0 |
| 35995342 | 2022 | Association of complement component 4 with neuroimmune abnormalities in the subventricular zone in schizophrenia and autism spectrum disorders. | 4 |
Citation
Dessen P
C4A (complement C4A (Rodgers blood group))
Atlas Genet Cytogenet Oncol Haematol. 2009-05-01
Online version: http://atlasgeneticsoncology.org/gene/50897/c4a
