Identity
HGNC
LOCATION
8q12.1
LOCUSID
ALIAS
CA-RP,CA-VIII,CALS,CAMRQ3,CARP
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 767
MIM: 114815
HGNC: 1382
Ensembl: ENSG00000178538
Variants:
dbSNP: 767
ClinVar: 767
TCGA: ENSG00000178538
COSMIC: CA8
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000178538 | ENST00000317995 | P35219 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Nitrogen metabolism | KEGG | ko00910 |
| Nitrogen metabolism | KEGG | hsa00910 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38571370 | 2024 | Effects of down-regulated carbonic anhydrase 8 on cell survival and glucose metabolism in human colorectal cancer cell lines. | 0 |
| 38571370 | 2024 | Effects of down-regulated carbonic anhydrase 8 on cell survival and glucose metabolism in human colorectal cancer cell lines. | 0 |
| 35488942 | 2022 | Altered glucose metabolism and its association with carbonic anhydrase 8 in Machado-Joseph Disease. | 0 |
| 35901081 | 2022 | Carbonic anhydrase XII as biomarker and therapeutic target in ovarian carcinomas. | 0 |
| 35488942 | 2022 | Altered glucose metabolism and its association with carbonic anhydrase 8 in Machado-Joseph Disease. | 0 |
| 35901081 | 2022 | Carbonic anhydrase XII as biomarker and therapeutic target in ovarian carcinomas. | 0 |
| 32583043 | 2021 | Expression and Functional Study of Single Mutations of Carbonic Anhydrase 8 in Neuronal Cells. | 1 |
| 32583043 | 2021 | Expression and Functional Study of Single Mutations of Carbonic Anhydrase 8 in Neuronal Cells. | 1 |
| 31693170 | 2020 | Cerebellar ataxia with normal intellect associated with a homozygous truncating variant in CA8. | 0 |
| 31715371 | 2020 | CA8 promotes RCC proliferation and migration though its expression level is lower in tumor compared to adjacent normal tissue. | 10 |
| 33247772 | 2020 | Reversion mutation of cDNA CA8-204 minigene construct produces a truncated functional peptide that regulates calcium release in vitro and produces profound analgesia in vivo. | 2 |
| 31693170 | 2020 | Cerebellar ataxia with normal intellect associated with a homozygous truncating variant in CA8. | 0 |
| 31715371 | 2020 | CA8 promotes RCC proliferation and migration though its expression level is lower in tumor compared to adjacent normal tissue. | 10 |
| 33247772 | 2020 | Reversion mutation of cDNA CA8-204 minigene construct produces a truncated functional peptide that regulates calcium release in vitro and produces profound analgesia in vivo. | 2 |
| 31199789 | 2019 | Profound analgesia is associated with a truncated peptide resulting from tissue specific alternative splicing of DRG CA8-204 regulated by an exon-level cis-eQTL. | 5 |
Citation
Dessen P
CA8 (carbonic anhydrase 8)
Atlas Genet Cytogenet Oncol Haematol. 2007-07-01
Online version: http://atlasgeneticsoncology.org/gene/47616/ca8
