CAB39L (calcium binding protein 39 like)

2009-01-01  

Identity

HGNC
LOCATION
13q14.2
LOCUSID
ALIAS
MO25-BETA,MO2L,bA103J18.3

Other Information

Locus ID:

NCBI: 81617
MIM: 612175
HGNC: 20290
Ensembl: ENSG00000102547

Variants:

dbSNP: 81617
ClinVar: 81617
TCGA: ENSG00000102547
COSMIC: CAB39L

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000102547ENST00000347776Q9H9S4
ENSG00000102547ENST00000347776A0A024RDT3
ENSG00000102547ENST00000355854Q9H9S4
ENSG00000102547ENST00000355854A0A024RDT3
ENSG00000102547ENST00000409082B7ZBJ7
ENSG00000102547ENST00000409130B7ZBJ4
ENSG00000102547ENST00000409308Q9H9S4
ENSG00000102547ENST00000409308A0A024RDT3
ENSG00000102547ENST00000410043Q9H9S4
ENSG00000102547ENST00000410043A0A024RDT3
ENSG00000102547ENST00000413278B7ZBJ6
ENSG00000102547ENST00000425242Q5TAW7
ENSG00000102547ENST00000457041B7ZBJ5
ENSG00000102547ENST00000610540Q9H9S4
ENSG00000102547ENST00000610540A0A024RDT3

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Pathways

PathwaySourceExternal ID
mTOR signaling pathwayKEGGko04150
mTOR signaling pathwayKEGGhsa04150
AMPK signaling pathwayKEGGhsa04152
AMPK signaling pathwayKEGGko04152
Signal TransductionREACTOMER-HSA-162582
Signaling by Insulin receptorREACTOMER-HSA-74752
Insulin receptor signalling cascadeREACTOMER-HSA-74751
IRS-mediated signallingREACTOMER-HSA-112399
PI3K CascadeREACTOMER-HSA-109704
PKB-mediated eventsREACTOMER-HSA-109703
mTOR signallingREACTOMER-HSA-165159
Energy dependent regulation of mTOR by LKB1-AMPKREACTOMER-HSA-380972
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)REACTOMER-HSA-2404192
IGF1R signaling cascadeREACTOMER-HSA-2428924
IRS-related events triggered by IGF1RREACTOMER-HSA-2428928

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
386769262024Loss of LPAR6 and CAB39L dysregulates the basal-to-luminal urothelial differentiation program, contributing to bladder carcinogenesis.0
386769262024Loss of LPAR6 and CAB39L dysregulates the basal-to-luminal urothelial differentiation program, contributing to bladder carcinogenesis.0
371096742023Bioinformatics Prediction and Experimental Verification Identify CAB39L as a Diagnostic and Prognostic Biomarker of Kidney Renal Clear Cell Carcinoma.1
371096742023Bioinformatics Prediction and Experimental Verification Identify CAB39L as a Diagnostic and Prognostic Biomarker of Kidney Renal Clear Cell Carcinoma.1
335960232021Identification of HLA-A*0201-restricted CTL Epitopes for MLAA-34-specific Immunotherapy for Acute Monocytic Leukemia.0
335960232021Identification of HLA-A*0201-restricted CTL Epitopes for MLAA-34-specific Immunotherapy for Acute Monocytic Leukemia.0
317183292020Targeted silencing of genes related to acute monocytic leukaemia by CpG(B)-MLAA-34 siRNA conjugates.0
317183292020Targeted silencing of genes related to acute monocytic leukaemia by CpG(B)-MLAA-34 siRNA conjugates.0
312049112019[Cloning of New Antigen Gene MLAA-34 Promoter and Identification of Core Region in Acute Monocytic Leukemia].1
312049112019[Cloning of New Antigen Gene MLAA-34 Promoter and Identification of Core Region in Acute Monocytic Leukemia].1
300545622018CAB39L elicited an anti-Warburg effect via a LKB1-AMPK-PGC1α axis to inhibit gastric tumorigenesis.32
300545622018CAB39L elicited an anti-Warburg effect via a LKB1-AMPK-PGC1α axis to inhibit gastric tumorigenesis.32
263064672016Frameshift Mutations of CAB39L, an Activator of LKB1 Tumor Suppressor, in Gastric and Colorectal Cancers.2
263064672016Frameshift Mutations of CAB39L, an Activator of LKB1 Tumor Suppressor, in Gastric and Colorectal Cancers.2
231356222013The expression and functional characterization associated with cell apoptosis and proteomic analysis of the novel gene MLAA-34 in U937 cells.7

Citation

Dessen P

CAB39L (calcium binding protein 39 like)

Atlas Genet Cytogenet Oncol Haematol. 2009-01-01

Online version: http://atlasgeneticsoncology.org/gene/50657/cab39l