CACNG5 (calcium voltage-gated channel auxiliary subunit gamma 5)

2018-07-01  

Identity

HGNC
LOCATION
17q24.2
LOCUSID
ALIAS
-

Other Information

Locus ID:

NCBI: 27091
MIM: 606405
HGNC: 1409
Ensembl: ENSG00000075429

Variants:

dbSNP: 27091
ClinVar: 27091
TCGA: ENSG00000075429
COSMIC: CACNG5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000075429ENST00000307139Q9UF02
ENSG00000075429ENST00000533854Q9UF02

Expression (GTEx)

0
1

Pathways

PathwaySourceExternal ID
MAPK signaling pathwayKEGGko04010
MAPK signaling pathwayKEGGhsa04010
Cardiac muscle contractionKEGGhsa04260
Cardiac muscle contractionKEGGko04260
Hypertrophic cardiomyopathy (HCM)KEGGko05410
Hypertrophic cardiomyopathy (HCM)KEGGhsa05410
Arrhythmogenic right ventricular cardiomyopathy (ARVC)KEGGko05412
Arrhythmogenic right ventricular cardiomyopathy (ARVC)KEGGhsa05412
Dilated cardiomyopathyKEGGko05414
Dilated cardiomyopathyKEGGhsa05414
Adrenergic signaling in cardiomyocytesKEGGhsa04261
Adrenergic signaling in cardiomyocytesKEGGko04261
Oxytocin signaling pathwayKEGGhsa04921
Oxytocin signaling pathwayKEGGko04921
Muscle contractionREACTOMER-HSA-397014
Cardiac conductionREACTOMER-HSA-5576891
Phase 0 - rapid depolarisationREACTOMER-HSA-5576892
Phase 2 - plateau phaseREACTOMER-HSA-5576893

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
210573792011Case-case genome-wide association analysis shows markers differentially associated with schizophrenia and bipolar disorder and implicates calcium channel genes.22
271025622016Evaluation of voltage-dependent calcium channel γ gene families identified several novel potential susceptible genes to schizophrenia.18
292156992018LncRNA LINC00880 promotes cell proliferation, migration, and invasion while inhibiting apoptosis by targeting CACNG5 through the MAPK signaling pathway in spinal cord ependymoma.3

Citation

Dessen P

CACNG5 (calcium voltage-gated channel auxiliary subunit gamma 5)

Atlas Genet Cytogenet Oncol Haematol. 2018-07-01

Online version: http://atlasgeneticsoncology.org/gene/57495/cacng5