CADM1 (cell adhesion molecule 1)

2003-02-01  

Identity

HGNC
LOCATION
11q23.3
LOCUSID
ALIAS
BL2,IGSF4,IGSF4A,NECL2,Necl-2,RA175,ST17,SYNCAM,TSLC1,sTSLC-1,sgIGSF,synCAM1
FUSION GENES

Other Information

Locus ID:

NCBI: 23705
MIM: 605686
HGNC: 5951
Ensembl: ENSG00000182985

Variants:

dbSNP: 23705
ClinVar: 23705
TCGA: ENSG00000182985
COSMIC: CADM1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000182985ENST00000331581Q9BY67
ENSG00000182985ENST00000331581X5D7A8
ENSG00000182985ENST00000452722Q9BY67
ENSG00000182985ENST00000452722X5D8W0
ENSG00000182985ENST00000536727X5DQS5
ENSG00000182985ENST00000537058Q9BY67
ENSG00000182985ENST00000537058X5DQR8
ENSG00000182985ENST00000540951F5H372
ENSG00000182985ENST00000542447Q9BY67
ENSG00000182985ENST00000542450F5H8J9
ENSG00000182985ENST00000543249H0YG94
ENSG00000182985ENST00000543540F5H0H5
ENSG00000182985ENST00000545094F5H125
ENSG00000182985ENST00000545380A0A0A0MTJ8
ENSG00000182985ENST00000612235A0A087X0T8
ENSG00000182985ENST00000616271A0A087X1W8

Expression (GTEx)

0
10
20
30
40
50
60
70

Pathways

PathwaySourceExternal ID
Cell adhesion molecules (CAMs)KEGGko04514
Cell adhesion molecules (CAMs)KEGGhsa04514
Cell-Cell communicationREACTOMER-HSA-1500931
Cell junction organizationREACTOMER-HSA-446728
Cell-cell junction organizationREACTOMER-HSA-421270
Adherens junctions interactionsREACTOMER-HSA-418990
Nectin/Necl trans heterodimerizationREACTOMER-HSA-420597

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
122028222002SynCAM, a synaptic adhesion molecule that drives synapse assembly.268
205709662010Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease.130
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
157814512005Nectin-like protein 2 defines a subset of T-cell zone dendritic cells and is a ligand for class-I-restricted T-cell-associated molecule.61
163110152006Bioinformatic characterization of the SynCAM family of immunoglobulin-like domain-containing adhesion molecules.55
149702782004TSLC1 gene silencing in cervical cancer cell lines and cervical neoplasia.53
158119522005The tumor suppressor TSLC1/NECL-2 triggers NK-cell and CD8+ T-cell responses through the cell-surface receptor CRTAM.49
213890982011Combined promoter methylation analysis of CADM1 and MAL: an objective triage tool for high-risk human papillomavirus DNA-positive women.48
154719562005Overexpression of a cell adhesion molecule, TSLC1, as a possible molecular marker for acute-type adult T-cell leukemia.44

Citation

Dessen P

CADM1 (cell adhesion molecule 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/40936/cadm1