CAPN7 (calpain 7)

2014-11-01  

Identity

HGNC
LOCATION
3p25.1
LOCUSID
ALIAS
CALPAIN7,PALBH
FUSION GENES

Other Information

Locus ID:

NCBI: 23473
MIM: 606400
HGNC: 1484
Ensembl: ENSG00000131375

Variants:

dbSNP: 23473
ClinVar: 23473
TCGA: ENSG00000131375
COSMIC: CAPN7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000131375ENST00000253693Q9Y6W3
ENSG00000131375ENST00000415565H7C1B7
ENSG00000131375ENST00000418994F8WCZ1
ENSG00000131375ENST00000443567H7C0F1
ENSG00000131375ENST00000457023F8WDQ3

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

Pathways

PathwaySourceExternal ID
Extracellular matrix organizationREACTOMER-HSA-1474244
Degradation of the extracellular matrixREACTOMER-HSA-1474228

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
208494182010Autolytic activity of human calpain 7 is enhanced by ESCRT-III-related protein IST1 through MIT-MIM interaction.11
238555902013CAPN 7 promotes the migration and invasion of human endometrial stromal cell by regulating matrix metalloproteinase 2 activity.6
249531352014Involvement of calpain-7 in epidermal growth factor receptor degradation via the endosomal sorting pathway.3
216169152011Calpain-7 binds to CHMP1B at its second α-helical region and forms a ternary complex with IST1.2
234971132013Analysis of limited proteolytic activity of calpain-7 using non-physiological substrates in mammalian cells.1

Citation

Dessen P

CAPN7 (calpain 7)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/61410/capn7