Identity
HGNC
LOCATION
7q34
LOCUSID
ALIAS
CASP-2,ICH1,NEDD-2,NEDD2,PPP1R57
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 835
MIM: 600639
HGNC: 1503
Ensembl: ENSG00000106144
Variants:
dbSNP: 835
ClinVar: 835
TCGA: ENSG00000106144
COSMIC: CASP2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37880421 | 2024 | Bi-allelic truncating variants in CASP2 underlie a neurodevelopmental disorder with lissencephaly. | 2 |
| 38429264 | 2024 | Caspase-2 protects against ferroptotic cell death. | 0 |
| 37880421 | 2024 | Bi-allelic truncating variants in CASP2 underlie a neurodevelopmental disorder with lissencephaly. | 2 |
| 38429264 | 2024 | Caspase-2 protects against ferroptotic cell death. | 0 |
| 36343883 | 2023 | Targeting caspase-2 interactions with tau in Alzheimer's disease and related dementias. | 2 |
| 36593108 | 2023 | Triglyceride induces DNA damage leading to monocyte death by activating caspase-2 and caspase-8. | 2 |
| 37086756 | 2023 | Dual truncation of tau by caspase-2 accelerates its CHIP-mediated degradation. | 1 |
| 36343883 | 2023 | Targeting caspase-2 interactions with tau in Alzheimer's disease and related dementias. | 2 |
| 36593108 | 2023 | Triglyceride induces DNA damage leading to monocyte death by activating caspase-2 and caspase-8. | 2 |
| 37086756 | 2023 | Dual truncation of tau by caspase-2 accelerates its CHIP-mediated degradation. | 1 |
| 35436510 | 2022 | miR-150-3p enhances neuroprotective effects of neural stem cell exosomes after hypoxic-ischemic brain injury by targeting CASP2. | 17 |
| 36129947 | 2022 | Caspase-2 mRNA levels are not elevated in mild cognitive impairment, Alzheimer's disease, Huntington's disease, or Lewy Body dementia. | 0 |
| 36379916 | 2022 | Genuine selective caspase-2 inhibition with new irreversible small peptidomimetics. | 1 |
| 35436510 | 2022 | miR-150-3p enhances neuroprotective effects of neural stem cell exosomes after hypoxic-ischemic brain injury by targeting CASP2. | 17 |
| 36129947 | 2022 | Caspase-2 mRNA levels are not elevated in mild cognitive impairment, Alzheimer's disease, Huntington's disease, or Lewy Body dementia. | 0 |
Citation
Dessen P
CASP2 (caspase 2)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/919/casp2
