CBX6 (chromobox 6)

2007-04-01  

Identity

HGNC
LOCATION
22q13.1
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 23466
MIM: 617438
HGNC: 1556
Ensembl: ENSG00000183741

Variants:

dbSNP: 23466
ClinVar: 23466
TCGA: ENSG00000183741
COSMIC: CBX6

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000183741ENST00000216083B0QXZ6
ENSG00000183741ENST00000407418O95503

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
Cellular responses to stressREACTOMER-HSA-2262752
Cellular SenescenceREACTOMER-HSA-2559583
Oxidative Stress Induced SenescenceREACTOMER-HSA-2559580

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
263433562015Polycomb genes are associated with response to imatinib in chronic myeloid leukemia.8
281223512017CBX6 overexpression contributes to tumor progression and is predictive of a poor prognosis in hepatocellular carcinoma.8
288391332017USP26 functions as a negative regulator of cellular reprogramming by stabilising PRC1 complex components.6
306555502019CBX6 is negatively regulated by EZH2 and plays a potential tumor suppressor role in breast cancer.1

Citation

Dessen P

CBX6 (chromobox 6)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/47138/cbx6