CCDC106 (coiled-coil domain containing 106)

2018-07-01  

Identity

HGNC
CCDC106
LOCATION
19q13.42
LOCUSID
29903
ALIAS
HSU79303,ZNF581
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 29903
MIM: 613478
HGNC: 30181
Ensembl: ENSG00000173581

Variants:

dbSNP: 29903
ClinVar: 29903
TCGA: ENSG00000173581
COSMIC: CCDC106

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000173581ENST00000308964Q9BWC9
ENSG00000173581ENST00000586790Q9BWC9
ENSG00000173581ENST00000587213K7ER22
ENSG00000173581ENST00000588740Q9BWC9
ENSG00000173581ENST00000591241K7EMI9
ENSG00000173581ENST00000591578Q9BWC9
ENSG00000173581ENST00000592996K7EMP7
ENSG00000173581ENST00000593069K7ES29

Expression (GTEx)

0
10
20
30
40
50
60
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
201590182010Identification and characterization of the novel protein CCDC106 that interacts with p53 and promotes its degradation.7
284604552017CCDC106 promotes non-small cell lung cancer cell proliferation.5
308852512019CK2-mediated CCDC106 phosphorylation is required for p53 degradation in cancer progression.1

Citation

Dessen P

CCDC106 (coiled-coil domain containing 106)

Atlas Genet Cytogenet Oncol Haematol. 2018-07-01

Online version: http://atlasgeneticsoncology.org/gene/57436/ccdc106