CCDC50 (coiled-coil domain containing 50)

2010-01-01  

Identity

HGNC
LOCATION
3q28
LOCUSID
ALIAS
C3orf6,DFNA44,YMER
FUSION GENES

Other Information

Locus ID:

NCBI: 152137
MIM: 611051
HGNC: 18111
Ensembl: ENSG00000152492

Variants:

dbSNP: 152137
ClinVar: 152137
TCGA: ENSG00000152492
COSMIC: CCDC50

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000152492ENST00000392455Q8IVM0
ENSG00000152492ENST00000392456Q8IVM0

Expression (GTEx)

0
10
20
30
40
50
60

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
379653132023Molecular profiling of clinical remission in psoriatic arthritis reveals dysregulation of FOS and CCDC50 genes: a gene expression study.0
379653132023Molecular profiling of clinical remission in psoriatic arthritis reveals dysregulation of FOS and CCDC50 genes: a gene expression study.0
326122002021A novel selective autophagy receptor, CCDC50, delivers K63 polyubiquitination-activated RIG-I/MDA5 for degradation during viral infection.45
344531262021Autophagy receptor CCDC50 tunes the STING-mediated interferon response in viral infections and autoimmune diseases.17
326122002021A novel selective autophagy receptor, CCDC50, delivers K63 polyubiquitination-activated RIG-I/MDA5 for degradation during viral infection.45
344531262021Autophagy receptor CCDC50 tunes the STING-mediated interferon response in viral infections and autoimmune diseases.17
332776102020Coiled-coil domain containing 50-V2 protein positively regulates neurite outgrowth.0
332776102020Coiled-coil domain containing 50-V2 protein positively regulates neurite outgrowth.0
271429902016Research progress in pathogenic genes of hereditary non-syndromic mid-frequency deafness.6
271429902016Research progress in pathogenic genes of hereditary non-syndromic mid-frequency deafness.6
223310272012Ymer acts as a multifunctional regulator in nuclear factor-κB and Fas signaling pathways.9
223310272012Ymer acts as a multifunctional regulator in nuclear factor-κB and Fas signaling pathways.9
190592082009Inhibition of NF-kappaB signaling via tyrosine phosphorylation of Ymer.9
196415242009Gene knockdown studies revealed CCDC50 as a candidate gene in mantle cell lymphoma and chronic lymphocytic leukemia.21
190592082009Inhibition of NF-kappaB signaling via tyrosine phosphorylation of Ymer.9

Citation

Dessen P

CCDC50 (coiled-coil domain containing 50)

Atlas Genet Cytogenet Oncol Haematol. 2010-01-01

Online version: http://atlasgeneticsoncology.org/gene/51303/ccdc50