CCL14 (C-C motif chemokine ligand 14)

2003-05-01  

Identity

HGNC
LOCATION
17q12
LOCUSID
ALIAS
CC-1,CC-3,CKB1,HCC-1,HCC-1(1-74),HCC-1/HCC-3,HCC-3,MCIF,NCC-2,NCC2,SCYA14,SCYL2,SY14

Other Information

Locus ID:

NCBI: 6358
MIM: 601392
HGNC: 10612
Ensembl: ENSG00000276409

Variants:

dbSNP: 6358
ClinVar: 6358
TCGA: ENSG00000276409
COSMIC: CCL14

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000276409ENST00000614009A0A087X089
ENSG00000276409ENST00000618404Q16627
ENSG00000276409ENST00000620991A0A0B4J2G5
ENSG00000276409ENST00000622526Q16627

Expression (GTEx)

0
50
100
150
200

Pathways

PathwaySourceExternal ID
Cytokine-cytokine receptor interactionKEGGko04060
Cytokine-cytokine receptor interactionKEGGhsa04060
Chemokine signaling pathwayKEGGko04062
Chemokine signaling pathwayKEGGhsa04062

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
364090282023Chemokine CCL14 affected the clinical outcome and correlated with immune infiltrates in thyroid carcinoma.3
375966982023Performance of urinary C-C motif chemokine ligand 14 for the prediction of persistent acute kidney injury: a systematic review and meta-analysis.2
364090282023Chemokine CCL14 affected the clinical outcome and correlated with immune infiltrates in thyroid carcinoma.3
375966982023Performance of urinary C-C motif chemokine ligand 14 for the prediction of persistent acute kidney injury: a systematic review and meta-analysis.2
359733972022CCL14 exacerbates intraplaque vulnerability by promoting neovascularization in the human carotid plaque.1
359733972022CCL14 exacerbates intraplaque vulnerability by promoting neovascularization in the human carotid plaque.1
331609902021Lysine demethylase 5B suppresses CC chemokine ligand 14 to promote progression of colorectal cancer through the Wnt/β-catenin pathway.11
339889672021Glycosylation Regulates N-Terminal Proteolysis and Activity of the Chemokine CCL14.5
340966112021C-C motif chemokine ligand 14 inhibited colon cancer cell proliferation and invasion through suppressing M2 polarization of tumor-associated macrophages.3
331609902021Lysine demethylase 5B suppresses CC chemokine ligand 14 to promote progression of colorectal cancer through the Wnt/β-catenin pathway.11
339889672021Glycosylation Regulates N-Terminal Proteolysis and Activity of the Chemokine CCL14.5
340966112021C-C motif chemokine ligand 14 inhibited colon cancer cell proliferation and invasion through suppressing M2 polarization of tumor-associated macrophages.3
316820092020Whole transcriptome analysis of smoker palatal mucosa identifies multiple downregulated innate immunity genes.2
319098952020Serum proteins TGFBI, PCSK9, and CCL14 are potential biomarkers for different traditional Chinese medicine syndromes of multidrug-resistant tuberculosis.1
316820092020Whole transcriptome analysis of smoker palatal mucosa identifies multiple downregulated innate immunity genes.2

Citation

Dessen P

CCL14 (C-C motif chemokine ligand 14)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/940/ccl14