CCL26 (C-C motif chemokine ligand 26)

2010-10-01 Affiliation

Identity

HGNC

CCL26

LOCATION

7q11.23

LOCUSID

10344

ALIAS

IMAC,MIP-4a,MIP-4alpha,SCYA26,TSC-1

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 10344
MIM: 604697
HGNC: 10625
Ensembl: ENSG00000006606

Variants:

dbSNP: 10344
ClinVar: 10344
TCGA: ENSG00000006606
COSMIC: CCL26

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000006606	ENST00000005180	Q9Y258
ENSG00000006606	ENST00000394905	Q9Y258

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Cytokine-cytokine receptor interaction	KEGG	ko04060
Cytokine-cytokine receptor interaction	KEGG	hsa04060
Chemokine signaling pathway	KEGG	ko04062
Chemokine signaling pathway	KEGG	hsa04062

References

Pubmed ID	Year	Title	Citations
16453027	2006	Eotaxin-3 and a uniquely conserved gene-expression profile in eosinophilic esophagitis.	255
17703412	2007	Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes.	100
22580413	2013	Omeprazole blocks eotaxin-3 expression by oesophageal squamous cells from patients with eosinophilic oesophagitis and GORD.	92
23185525	2012	Omeprazole blocks STAT6 binding to the eotaxin-3 promoter in eosinophilic esophagitis cells.	66
17900656	2007	Increased expression of eotaxin-3 distinguishes between eosinophilic esophagitis and gastroesophageal reflux disease.	37
16084752	2005	Eotaxin-3/CCL26 gene expression in intestinal epithelial cells is up-regulated by interleukin-4 and interleukin-13 via the signal transducer and activator of transcription 6.	33
27228567	2016	Hypoxia induces myeloid-derived suppressor cell recruitment to hepatocellular carcinoma through chemokine (C-C motif) ligand 26.	32
20974991	2010	Eotaxin-3/CC chemokine ligand 26 is a functional ligand for CX3CR1.	27
18844613	2008	Treatment with topical steroids downregulates IL-5, eotaxin-1/CCL11, and eotaxin-3/CCL26 gene expression in eosinophilic esophagitis.	26
19258923	2009	Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes.	26

Citation

Dessen P

CCL26 (C-C motif chemokine ligand 26)

Atlas Genet Cytogenet Oncol Haematol. 2010-10-01

Online version: http://atlasgeneticsoncology.org/gene/51681/ccl26