Atlas of Genetics and Cytogenetics in Oncology and Haematology

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   
X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

CCND2 (cyclin D2)

Identity

Other namesKIAK0002
MGC102758
HGNC (Hugo) CCND2
Location 12p13.32
Location_base_pair Starts at 4253163 and ends at 4284782 bp from pter ( according to hg18-March_2006)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Breakpoints

 

External links

Nomenclature
HGNC (Hugo)CCND2   1583
Entrez_Gene (NCBI)CCND2  894  cyclin D2
Cards
GeneCards (Weizmann)CCND2
Ensembl (Hinxton)ENSG00000118971 [Gene_View]  CCND2 [Vega]
AceView (NCBI)CCND2
Genatlas (Paris)CCND2
euGene (Indiana)894
SOURCE (Stanford)NM_001759
Gene Expression (Array Express) ENSG00000118971
Genomic and cartography
GoldenPath (UCSC)CCND2  -  12p13.32   chr12:4253163-4284782 +  12p13.32   [Description]    (hg18-March_2006)
EnsemblCCND2 - 12p13.32 [CytoView]
Mapping of homologs : NCBICCND2 [Mapview]
OMIM123833   
Gene and transcription
Gene : Genbank (Entrez)AI055922 AK223577 AK291146 BC010958 BC014357
Reference sequence (RefSeq transcript) :SRSNM_001759
Reference transcript : EntrezNM_001759
RefSeq genomic : SRSAC_000055 AC_000144 NC_000012 NT_009759 NW_001838049 NW_925295
RefSeq genomic : EntrezAC_000055 AC_000144 NC_000012 NT_009759 NW_001838049 NW_925295
Consensus coding sequences : CCDS NCBICCND2
Cluster EST : UnigeneHs.376071 [ SRS ] Hs.376071 [ NCBI ]
Alternative Splicing : Fast-db (Paris)689
Protein : pattern, domain, 3D structure
Protein : UniProt/SwissProtP30279 (SRS) P30279 (Expasy) P30279 (Uniprot)
With graphics : InterProP30279
Splice isoforms : VarSplice FASTAP30279(VarSplice FASTA)
Domaine pattern : Prosite (SRS)CYCLINS (PS00292)   
Domain pattern : Prosite (Expaxy)CYCLINS (PS00292)   
Domains : Interpro (SRS)CycD    Cyclin    Cyclin-like    Cyclin_A_B_D_E    Cyclin_C    Cyclin_N    Cyclin_related   
Domains : Interpro (EBI)CycD    Cyclin    Cyclin-like    Cyclin_A_B_D_E    Cyclin_C    Cyclin_N    Cyclin_related   
Related proteins : CluSTrP30279
Domain families : Pfam SRSCyclin_C (PF02984)    Cyclin_N (PF00134)   
Domain families : Pfam SangerCyclin_C (PF02984)    Cyclin_N (PF00134)   
Domain families : Pfam NCBIpfam02984    pfam00134   
Domain families : Smart EMBLCYCLIN (SM00385)  
Blocks (Seattle)P30279
Crystal structure of protein : PDB SRS
Crystal structure of protein : PDBSum
Crystal structure of protein : IMB
Crystal structure of protein : PDB RSDB
HPRD00451
Protein Interaction databases
DIP (DOE-UCLA)P30279
IntAct (EBI)P30279
Polymorphism : SNP, mutations, diseases
Single Nucleotide Polymorphism (SNP) : dbSNP NCBICCND2
SNP : GeneSNP UtahCCND2
SNP : HGBaseCCND2
Genetic variants : HAPMAPCCND2
Cancer Gene: CensusCCND2 
Somatic Mutations in Cancer : COSMICCCND2 
Mutations and Diseases : HGMDCCND2
Hereditary diseases : OMIM123833   
Hereditary diseases : GENETests123833   
Diseases : Genetic AssociationCCND2
General knowledge
Homologs : HomoloGeneCCND2
Homology/Alignments : Family Browser UCSCCCND2
Phylogenetic Trees/Animal Genes : TreeFamCCND2
Chemical/Protein Interactions : CTD894
Keywords Ontology : AmiGOcyclin-dependent protein kinase holoenzyme complex  ovarian follicle development  liver development  positive regulation of protein amino acid phosphorylation  protein binding  nucleus  spermatogenesis  response to organic cyclic substance  protein kinase binding  response to estradiol stimulus  cellular response to insulin stimulus  response to testosterone stimulus  response to peptide hormone stimulus  response to ethanol  regulation of neuron differentiation  positive regulation of cyclin-dependent protein kinase activity  positive regulation of epithelial cell proliferation  cell division  response to cAMP  regulation of cell cycle  
Keywords Ontology : EGO-EBIcyclin-dependent protein kinase holoenzyme complex  ovarian follicle development  liver development  positive regulation of protein amino acid phosphorylation  protein binding  nucleus  spermatogenesis  response to organic cyclic substance  protein kinase binding  response to estradiol stimulus  cellular response to insulin stimulus  response to testosterone stimulus  response to peptide hormone stimulus  response to ethanol  regulation of neuron differentiation  positive regulation of cyclin-dependent protein kinase activity  positive regulation of epithelial cell proliferation  cell division  response to cAMP  regulation of cell cycle  
Pathways : BIOCARTACyclins and Cell Cycle Regulation [Genes]   
Pathways : KEGGCell cycleWnt signaling pathwayFocal adhesionJak-STAT signaling pathway
Other databases
Probes
Probes : ImagenesCCND2 Related clones (RZPD - Berlin)
Literature
PubMed82 Pubmed reference(s) in Entrez
PubGeneCCND2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated03-2009Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Feb 27 10:45:14 CET 2010
Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.