Atlas of Genetics and Cytogenetics in Oncology and Haematology

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CD1C (CD1c molecule)

Identity

Alias (NCBI)BDCA1
CD1
CD1A
R7
HGNC (Hugo) CD1C
HGNC Previous nameCD1
HGNC Previous nameCD1C antigen, c polypeptide
 CD1c antigen
LocusID (NCBI) 911
Atlas_Id 45607
Location 1q23.1  [Link to chromosome band 1q23]
Location_base_pair Starts at 158289923 and ends at 158294774 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CD1C (1q23.1) / CAMTA1 (1p36.31)JA040725 () / CD1C (1q23.1)NEK7 (1q31.3) / CD1C (1q23.1)
SLAMF1 (1q23.3) / CD1C (1q23.1)NEK7 1q31.3 / CD1C 1q23.1SLAMF1 1q23.3 / CD1C 1q23.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 2 ]
  SLAMF1/CD1C (1q23)
t(1;1)(q23;q31) NEK7/CD1C

External links

Nomenclature
HGNC (Hugo)CD1C   1636
Cards
Entrez_Gene (NCBI)CD1C  911  CD1c molecule
AliasesBDCA1; CD1; CD1A; R7
GeneCards (Weizmann)CD1C
Ensembl hg19 (Hinxton)ENSG00000158481 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000158481 [Gene_View]  ENSG00000158481 [Sequence]  chr1:158289923-158294774 [Contig_View]  CD1C [Vega]
ICGC DataPortalENSG00000158481
TCGA cBioPortalCD1C
AceView (NCBI)CD1C
Genatlas (Paris)CD1C
WikiGenes911
SOURCE (Princeton)CD1C
Genetics Home Reference (NIH)CD1C
Genomic and cartography
GoldenPath hg38 (UCSC)CD1C  -     chr1:158289923-158294774 +  1q23.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CD1C  -     1q23.1   [Description]    (hg19-Feb_2009)
GoldenPathCD1C - 1q23.1 [CytoView hg19]  CD1C - 1q23.1 [CytoView hg38]
ImmunoBaseENSG00000158481
genome Data Viewer NCBICD1C [Mapview hg19]  
OMIM188340   
Gene and transcription
Genbank (Entrez)AA824381 AK226024 AK298234 AK310577 AK310710
RefSeq transcript (Entrez)NM_001765
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CD1C
Alternative Splicing GalleryENSG00000158481
Gene ExpressionCD1C [ NCBI-GEO ]   CD1C [ EBI - ARRAY_EXPRESS ]   CD1C [ SEEK ]   CD1C [ MEM ]
Gene Expression Viewer (FireBrowse)CD1C [ Firebrowse - Broad ]
GenevisibleExpression of CD1C in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)911
GTEX Portal (Tissue expression)CD1C
Human Protein AtlasENSG00000158481-CD1C [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP29017   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP29017  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP29017
Splice isoforms : SwissVarP29017
PhosPhoSitePlusP29017
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)   
Domains : Interpro (EBI)Ig-like_dom    Ig-like_dom_sf    Ig-like_fold    Ig_C1-set    MHC_I-like_Ag-recog    MHC_I-like_Ag-recog_sf    MHC_I/II-like_Ag-recog   
Domain families : Pfam (Sanger)C1-set (PF07654)    MHC_I_3 (PF16497)   
Domain families : Pfam (NCBI)pfam07654    pfam16497   
Domain families : Smart (EMBL)IGc1 (SM00407)  
Conserved Domain (NCBI)CD1C
DMDM Disease mutations911
Blocks (Seattle)CD1C
PDB (RSDB)3OV6    4ONO    5C9J    6C09    6C15   
PDB Europe3OV6    4ONO    5C9J    6C09    6C15   
PDB (PDBSum)3OV6    4ONO    5C9J    6C09    6C15   
PDB (IMB)3OV6    4ONO    5C9J    6C09    6C15   
Structural Biology KnowledgeBase3OV6    4ONO    5C9J    6C09    6C15   
SCOP (Structural Classification of Proteins)3OV6    4ONO    5C9J    6C09    6C15   
CATH (Classification of proteins structures)3OV6    4ONO    5C9J    6C09    6C15   
SuperfamilyP29017
Human Protein Atlas [tissue]ENSG00000158481-CD1C [tissue]
Peptide AtlasP29017
HPRD01772
IPIIPI00019850   IPI01014577   IPI00514282   
Protein Interaction databases
DIP (DOE-UCLA)P29017
IntAct (EBI)P29017
FunCoupENSG00000158481
BioGRIDCD1C
STRING (EMBL)CD1C
ZODIACCD1C
Ontologies - Pathways
QuickGOP29017
Ontology : AmiGOpositive regulation of T cell mediated cytotoxicity  adaptive immune response  T cell activation involved in immune response  extracellular space  lysosome  plasma membrane  plasma membrane  integral component of plasma membrane  immune response  external side of plasma membrane  endosome membrane  endogenous lipid antigen binding  endogenous lipid antigen binding  exogenous lipid antigen binding  exogenous lipid antigen binding  antigen processing and presentation, endogenous lipid antigen via MHC class Ib  antigen processing and presentation, exogenous lipid antigen via MHC class Ib  regulation of immune response  glycolipid binding  lipopeptide binding  lipopeptide binding  
Ontology : EGO-EBIpositive regulation of T cell mediated cytotoxicity  adaptive immune response  T cell activation involved in immune response  extracellular space  lysosome  plasma membrane  plasma membrane  integral component of plasma membrane  immune response  external side of plasma membrane  endosome membrane  endogenous lipid antigen binding  endogenous lipid antigen binding  exogenous lipid antigen binding  exogenous lipid antigen binding  antigen processing and presentation, endogenous lipid antigen via MHC class Ib  antigen processing and presentation, exogenous lipid antigen via MHC class Ib  regulation of immune response  glycolipid binding  lipopeptide binding  lipopeptide binding  
Pathways : KEGGHematopoietic cell lineage   
NDEx NetworkCD1C
Atlas of Cancer Signalling NetworkCD1C
Wikipedia pathwaysCD1C
Orthology - Evolution
OrthoDB911
GeneTree (enSembl)ENSG00000158481
Phylogenetic Trees/Animal Genes : TreeFamCD1C
HOGENOMP29017
Homologs : HomoloGeneCD1C
Homology/Alignments : Family Browser (UCSC)CD1C
Gene fusions - Rearrangements
Fusion : MitelmanNEK7/CD1C [1q31.3/1q23.1]  
Fusion : MitelmanSLAMF1/CD1C [1q23.3/1q23.1]  
Fusion PortalNEK7 1q31.3 CD1C 1q23.1 PRAD
Fusion PortalSLAMF1 1q23.3 CD1C 1q23.1 LUAD
Fusion Cancer (Beijing)JA040725 [CD1C]  -  1q23.1 [FUSC001181]
Fusion : QuiverCD1C
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCD1C [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CD1C
dbVarCD1C
ClinVarCD1C
MonarchCD1C
1000_GenomesCD1C 
Exome Variant ServerCD1C
GNOMAD BrowserENSG00000158481
Varsome BrowserCD1C
Genetic variants : HAPMAP911
Genomic Variants (DGV)CD1C [DGVbeta]
DECIPHERCD1C [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCD1C 
Mutations
ICGC Data PortalCD1C 
TCGA Data PortalCD1C 
Broad Tumor PortalCD1C
OASIS PortalCD1C [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCD1C  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DCD1C
Mutations and Diseases : HGMDCD1C
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CD1C
DgiDB (Drug Gene Interaction Database)CD1C
DoCM (Curated mutations)CD1C (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CD1C (select a term)
intoGenCD1C
Cancer3DCD1C(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM188340   
Orphanet
DisGeNETCD1C
MedgenCD1C
Genetic Testing Registry CD1C
NextProtP29017 [Medical]
TSGene911
GENETestsCD1C
Target ValidationCD1C
Huge Navigator CD1C [HugePedia]
snp3D : Map Gene to Disease911
BioCentury BCIQCD1C
ClinGenCD1C
Clinical trials, drugs, therapy
Protein Interactions : CTD911
Pharm GKB GenePA26195
Clinical trialCD1C
Miscellaneous
canSAR (ICR)CD1C (select the gene name)
HarmonizomeCD1C
DataMed IndexCD1C
Probes
Litterature
PubMed59 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCD1C
EVEXCD1C
GoPubMedCD1C
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Sep 14 14:05:00 CEST 2020
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