Atlas of Genetics and Cytogenetics in Oncology and Haematology

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CD2BP2 (CD2 cytoplasmic tail binding protein 2)

Identity

Alias_namesCD2 antigen (cytoplasmic tail)-binding protein 2
CD2 (cytoplasmic tail) binding protein 2
Alias_symbol (synonym)LIN1
Snu40
PPP1R59
Other aliasFWP010
U5-52K
HGNC (Hugo) CD2BP2
LocusID (NCBI) 10421
Atlas_Id 61618
Location 16p11.2  [Link to chromosome band 16p11]
Location_base_pair Starts at 30350766 and ends at 30354934 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
INPPL1 (11q13.4) / CD2BP2 (16p11.2)TNFAIP2 (14q32.32) / CD2BP2 (16p11.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)CD2BP2   1656
Cards
Entrez_Gene (NCBI)CD2BP2  10421  CD2 cytoplasmic tail binding protein 2
AliasesFWP010; LIN1; PPP1R59; Snu40; 
U5-52K
GeneCards (Weizmann)CD2BP2
Ensembl hg19 (Hinxton)ENSG00000169217 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000169217 [Gene_View]  ENSG00000169217 [Sequence]  chr16:30350766-30354934 [Contig_View]  CD2BP2 [Vega]
ICGC DataPortalENSG00000169217
TCGA cBioPortalCD2BP2
AceView (NCBI)CD2BP2
Genatlas (Paris)CD2BP2
WikiGenes10421
SOURCE (Princeton)CD2BP2
Genetics Home Reference (NIH)CD2BP2
Genomic and cartography
GoldenPath hg38 (UCSC)CD2BP2  -     chr16:30350766-30354934 -  16p11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CD2BP2  -     16p11.2   [Description]    (hg19-Feb_2009)
GoldenPathCD2BP2 - 16p11.2 [CytoView hg19]  CD2BP2 - 16p11.2 [CytoView hg38]
ImmunoBaseENSG00000169217
Mapping of homologs : NCBICD2BP2 [Mapview hg19]  CD2BP2 [Mapview hg38]
OMIM604470   
Gene and transcription
Genbank (Entrez)AB033004 AF104222 AF109192 AK315708 BC000495
RefSeq transcript (Entrez)NM_001243646 NM_006110
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CD2BP2
Cluster EST : UnigeneHs.202677 [ NCBI ]
CGAP (NCI)Hs.202677
Alternative Splicing GalleryENSG00000169217
Gene ExpressionCD2BP2 [ NCBI-GEO ]   CD2BP2 [ EBI - ARRAY_EXPRESS ]   CD2BP2 [ SEEK ]   CD2BP2 [ MEM ]
Gene Expression Viewer (FireBrowse)CD2BP2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10421
GTEX Portal (Tissue expression)CD2BP2
Human Protein AtlasENSG00000169217-CD2BP2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95400   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95400  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95400
Splice isoforms : SwissVarO95400
PhosPhoSitePlusO95400
Domaine pattern : Prosite (Expaxy)GYF (PS50829)   
Domains : Interpro (EBI)GYF    GYF-like_dom_sf   
Domain families : Pfam (Sanger)GYF (PF02213)   
Domain families : Pfam (NCBI)pfam02213   
Domain families : Smart (EMBL)GYF (SM00444)  
Conserved Domain (NCBI)CD2BP2
DMDM Disease mutations10421
Blocks (Seattle)CD2BP2
PDB (RSDB)1GYF    1L2Z    1SYX    4BWS   
PDB Europe1GYF    1L2Z    1SYX    4BWS   
PDB (PDBSum)1GYF    1L2Z    1SYX    4BWS   
PDB (IMB)1GYF    1L2Z    1SYX    4BWS   
Structural Biology KnowledgeBase1GYF    1L2Z    1SYX    4BWS   
SCOP (Structural Classification of Proteins)1GYF    1L2Z    1SYX    4BWS   
CATH (Classification of proteins structures)1GYF    1L2Z    1SYX    4BWS   
SuperfamilyO95400
Human Protein Atlas [tissue]ENSG00000169217-CD2BP2 [tissue]
Peptide AtlasO95400
HPRD05127
IPIIPI00006103   
Protein Interaction databases
DIP (DOE-UCLA)O95400
IntAct (EBI)O95400
FunCoupENSG00000169217
BioGRIDCD2BP2
STRING (EMBL)CD2BP2
ZODIACCD2BP2
Ontologies - Pathways
QuickGOO95400
Ontology : AmiGOspliceosomal tri-snRNP complex assembly  mRNA splicing, via spliceosome  fibrillar center  protein binding  nucleus  nucleoplasm  nucleoplasm  U5 snRNP  U5 snRNP  cytoplasm  cytosol  negative regulation of phosphatase activity  nuclear speck  nuclear speck  ribonucleoprotein complex binding  U4/U6 x U5 tri-snRNP complex  
Ontology : EGO-EBIspliceosomal tri-snRNP complex assembly  mRNA splicing, via spliceosome  fibrillar center  protein binding  nucleus  nucleoplasm  nucleoplasm  U5 snRNP  U5 snRNP  cytoplasm  cytosol  negative regulation of phosphatase activity  nuclear speck  nuclear speck  ribonucleoprotein complex binding  U4/U6 x U5 tri-snRNP complex  
NDEx NetworkCD2BP2
Atlas of Cancer Signalling NetworkCD2BP2
Wikipedia pathwaysCD2BP2
Orthology - Evolution
OrthoDB10421
GeneTree (enSembl)ENSG00000169217
Phylogenetic Trees/Animal Genes : TreeFamCD2BP2
HOGENOMO95400
Homologs : HomoloGeneCD2BP2
Homology/Alignments : Family Browser (UCSC)CD2BP2
Gene fusions - Rearrangements
Fusion : QuiverCD2BP2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCD2BP2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CD2BP2
dbVarCD2BP2
ClinVarCD2BP2
1000_GenomesCD2BP2 
Exome Variant ServerCD2BP2
ExAC (Exome Aggregation Consortium)ENSG00000169217
GNOMAD BrowserENSG00000169217
Varsome BrowserCD2BP2
Genetic variants : HAPMAP10421
Genomic Variants (DGV)CD2BP2 [DGVbeta]
DECIPHERCD2BP2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCD2BP2 
Mutations
ICGC Data PortalCD2BP2 
TCGA Data PortalCD2BP2 
Broad Tumor PortalCD2BP2
OASIS PortalCD2BP2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCD2BP2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DCD2BP2
Mutations and Diseases : HGMDCD2BP2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CD2BP2
DgiDB (Drug Gene Interaction Database)CD2BP2
DoCM (Curated mutations)CD2BP2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CD2BP2 (select a term)
intoGenCD2BP2
Cancer3DCD2BP2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604470   
Orphanet
DisGeNETCD2BP2
MedgenCD2BP2
Genetic Testing Registry CD2BP2
NextProtO95400 [Medical]
TSGene10421
GENETestsCD2BP2
Target ValidationCD2BP2
Huge Navigator CD2BP2 [HugePedia]
snp3D : Map Gene to Disease10421
BioCentury BCIQCD2BP2
ClinGenCD2BP2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10421
Chemical/Pharm GKB GenePA26209
Clinical trialCD2BP2
Miscellaneous
canSAR (ICR)CD2BP2 (select the gene name)
DataMed IndexCD2BP2
Probes
Litterature
PubMed60 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCD2BP2
EVEXCD2BP2
GoPubMedCD2BP2
iHOPCD2BP2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Sep 3 15:23:20 CEST 2019
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