CD300LB (CD300 molecule like family member b)

2014-11-01 Affiliation

Identity

HGNC

CD300LB

LOCATION

17q25.1

LOCUSID

124599

ALIAS

CD300b,CLM-7,CLM7,CMRF35-A2,IREM-3,IREM3,TREM-5,TREM5

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 124599
MIM: 610705
HGNC: 30811
Ensembl: ENSG00000178789

Variants:

dbSNP: 124599
ClinVar: 124599
TCGA: ENSG00000178789
COSMIC: CD300LB

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000178789	ENST00000314401	J9JID3
ENSG00000178789	ENST00000392621	A8K4G0

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Immune System	REACTOME	R-HSA-168256
Adaptive Immune System	REACTOME	R-HSA-1280218
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	REACTOME	R-HSA-198933
Innate Immune System	REACTOME	R-HSA-168249
DAP12 interactions	REACTOME	R-HSA-2172127

References

Pubmed ID	Year	Title	Citations
20379614	2010	Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.	62
20237496	2010	New genetic associations detected in a host response study to hepatitis B vaccine.	27
17928527	2008	Analysis of mouse LMIR5/CLM-7 as an activating receptor: differential regulation of LMIR5/CLM-7 in mouse versus human cells.	20
16920917	2006	Molecular and functional characterization of CD300b, a new activating immunoglobulin receptor able to transduce signals through two different pathways.	16
27261276	2016	Lipopolysaccharide-Induced CD300b Receptor Binding to Toll-like Receptor 4 Alters Signaling to Drive Cytokine Responses that Enhance Septic Shock.	11
23072861	2013	CD300 molecule regulation of human dendritic cell functions.	8
28005267	2017	Human gingiva transcriptome during wound healing.	6

Citation

Dessen P

CD300LB (CD300 molecule like family member b)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/61621/cd300lb