CD34 (CD34 molecule)

2003-06-01  

Identity

HGNC
LOCATION
1q32.2
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 947
MIM: 142230
HGNC: 1662
Ensembl: ENSG00000174059

Variants:

dbSNP: 947
ClinVar: 947
TCGA: ENSG00000174059
COSMIC: CD34

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000174059ENST00000310833P28906
ENSG00000174059ENST00000356522P28906
ENSG00000174059ENST00000367036Q5JTA5

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
Cell adhesion molecules (CAMs)KEGGko04514
Hematopoietic cell lineageKEGGko04640
Cell adhesion molecules (CAMs)KEGGhsa04514
Hematopoietic cell lineageKEGGhsa04640
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cellREACTOMER-HSA-198933

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
218359082011Exosomes from human CD34(+) stem cells mediate their proangiogenic paracrine activity.198
217377872011Intramyocardial, autologous CD34+ cell therapy for refractory angina.151
170385032006Disseminated and sustained HIV infection in CD34+ cord blood cell-transplanted Rag2-/-gamma c-/- mice.119
164396882006CD34-/CD133+/VEGFR-2+ endothelial progenitor cell subpopulation with potent vasoregenerative capacities.71
212060862011Bald scalp in men with androgenetic alopecia retains hair follicle stem cells but lacks CD200-rich and CD34-positive hair follicle progenitor cells.71
192262222009Functional implications of CD34 expression in human adipose-derived stem/progenitor cells.64
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
206393922010Genome-wide association analysis identifies multiple loci related to resting heart rate.61
225819262012Sonic hedgehog-modified human CD34+ cells preserve cardiac function after acute myocardial infarction.57
221631202011CD34-positive stem cells: in the treatment of heart and vascular disease in human beings.55

Citation

Dessen P

CD34 (CD34 molecule)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/975/cd34