CD55 (CD55 molecule (Cromer blood group))

2003-11-01  

Identity

HGNC
LOCATION
1q32.2
LOCUSID
ALIAS
CHAPLE,CR,CROM,DAF,TC
FUSION GENES

Other Information

Locus ID:

NCBI: 1604
MIM: 125240
HGNC: 2665
Ensembl: ENSG00000196352

Variants:

dbSNP: 1604
ClinVar: 1604
TCGA: ENSG00000196352
COSMIC: CD55

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000196352ENST00000314754P08174
ENSG00000196352ENST00000343420H3BLV0
ENSG00000196352ENST00000367063B1AP13
ENSG00000196352ENST00000367064P08174
ENSG00000196352ENST00000367067H7BY55
ENSG00000196352ENST00000391921B1AP15
ENSG00000196352ENST00000618707A0A2R8YEC5
ENSG00000196352ENST00000634386A0A2R8Y4B4
ENSG00000196352ENST00000635614A0A2R8YDY3
ENSG00000196352ENST00000644836P08174
ENSG00000196352ENST00000645323P08174

Expression (GTEx)

0
50
100
150
200

Pathways

PathwaySourceExternal ID
Complement and coagulation cascadesKEGGko04610
Hematopoietic cell lineageKEGGko04640
Complement and coagulation cascadesKEGGhsa04610
Hematopoietic cell lineageKEGGhsa04640
Viral myocarditisKEGGhsa05416
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Asparagine N-linked glycosylationREACTOMER-HSA-446203
Transport to the Golgi and subsequent modificationREACTOMER-HSA-948021
ER to Golgi Anterograde TransportREACTOMER-HSA-199977
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Complement cascadeREACTOMER-HSA-166658
Regulation of Complement cascadeREACTOMER-HSA-977606
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR ligand bindingREACTOMER-HSA-500792
Class B/2 (Secretin family receptors)REACTOMER-HSA-373080
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
COPI-mediated anterograde transportREACTOMER-HSA-6807878
Neutrophil degranulationREACTOMER-HSA-6798695

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
126459512003Antigen-presenting cell exosomes are protected from complement-mediated lysis by expression of CD55 and CD59.75
188422942008Association between the SERPING1 gene and age-related macular degeneration: a two-stage case-control study.65
189970042009Widespread balancing selection and pathogen-driven selection at blood group antigen genes.54
178930772007FragAnchor: a large-scale predictor of glycosylphosphatidylinositol anchors in eukaryote protein sequences by qualitative scoring.53
161793712006Minor population of CD55-CD59- blood cells predicts response to immunosuppressive therapy and prognosis in patients with aplastic anemia.49
183050442008Hantavirus causing hemorrhagic fever with renal syndrome enters from the apical surface and requires decay-accelerating factor (DAF/CD55).42
145303742003Antiadhesive role of apical decay-accelerating factor (CD55) in human neutrophil transmigration across mucosal epithelia.37
197101322009Dynamin- and lipid raft-dependent entry of decay-accelerating factor (DAF)-binding and non-DAF-binding coxsackieviruses into nonpolarized cells.37
155360792005Molecular dissection of interactions between components of the alternative pathway of complement and decay accelerating factor (CD55).36
206738682010A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM).36

Citation

Dessen P

CD55 (CD55 molecule (Cromer blood group))

Atlas Genet Cytogenet Oncol Haematol. 2003-11-01

Online version: http://atlasgeneticsoncology.org/gene/40260/cd55