Identity
HGNC
LOCATION
17p13.1
LOCUSID
ALIAS
GP110,LAMP4,SCARD1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 968
MIM: 153634
HGNC: 1693
Ensembl: ENSG00000129226
Variants:
dbSNP: 968
ClinVar: 968
TCGA: ENSG00000129226
COSMIC: CD68
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000129226 | ENST00000250092 | P34810 |
| ENSG00000129226 | ENST00000380498 | P34810 |
| ENSG00000129226 | ENST00000584180 | J3KRX0 |
| ENSG00000129226 | ENST00000584502 | J3KT24 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Lysosome | KEGG | ko04142 |
| Lysosome | KEGG | hsa04142 |
| Immune System | REACTOME | R-HSA-168256 |
| Innate Immune System | REACTOME | R-HSA-168249 |
| Neutrophil degranulation | REACTOME | R-HSA-6798695 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38357542 | 2024 | Unraveling the potential of CD8, CD68, and VISTA as diagnostic and prognostic markers in patients with pancreatic ductal adenocarcinoma. | 3 |
| 38357542 | 2024 | Unraveling the potential of CD8, CD68, and VISTA as diagnostic and prognostic markers in patients with pancreatic ductal adenocarcinoma. | 3 |
| 36265573 | 2023 | A Retrospective Multicentric Study of 34 Patients with Niemann-Pick Type C Disease and Early Liver Involvement in France. | 1 |
| 36469034 | 2023 | Bone marrow expression of CD68/CD163 macrophages, IL-17 and FOXP3 cells in aplastic anemia and their relation to prognosis. | 2 |
| 36598153 | 2023 | CD47 and CD68 expression in breast cancer is associated with tumor-infiltrating lymphocytes, blood vessel invasion, detection mode, and prognosis. | 0 |
| 37118836 | 2023 | Microglial CD68 and L-ferritin upregulation in response to phosphorylated-TDP-43 pathology in the amyotrophic lateral sclerosis brain. | 6 |
| 37198277 | 2023 | Impact of vitamin D in children with chronic tonsillitis (immunohistochemical study of CD68 polarisation and proinflammatory cytokines estimation). | 1 |
| 38084523 | 2023 | CD68 expression in the placenta of gestational diabetic mothers: A case-control study. | 0 |
| 36265573 | 2023 | A Retrospective Multicentric Study of 34 Patients with Niemann-Pick Type C Disease and Early Liver Involvement in France. | 1 |
| 36469034 | 2023 | Bone marrow expression of CD68/CD163 macrophages, IL-17 and FOXP3 cells in aplastic anemia and their relation to prognosis. | 2 |
| 36598153 | 2023 | CD47 and CD68 expression in breast cancer is associated with tumor-infiltrating lymphocytes, blood vessel invasion, detection mode, and prognosis. | 0 |
| 37118836 | 2023 | Microglial CD68 and L-ferritin upregulation in response to phosphorylated-TDP-43 pathology in the amyotrophic lateral sclerosis brain. | 6 |
| 37198277 | 2023 | Impact of vitamin D in children with chronic tonsillitis (immunohistochemical study of CD68 polarisation and proinflammatory cytokines estimation). | 1 |
| 38084523 | 2023 | CD68 expression in the placenta of gestational diabetic mothers: A case-control study. | 0 |
| 35933009 | 2022 | Progranulin-derived granulin E and lysosome membrane protein CD68 interact to reciprocally regulate their protein homeostasis. | 2 |
Citation
Dessen P
CD68 (CD68 molecule)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/987/cd68
