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CDC34 (cell division cycle 34)

Identity

Other namesE2-CDC34
UBC3
UBCH3
UBE2R1
HGNC (Hugo) CDC34
LocusID (NCBI) 997
Atlas_Id 40010
Location 19p13.3
Location_base_pair Starts at 531733 and ends at 542087 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CDC34   1734
Cards
Entrez_Gene (NCBI)CDC34  997  cell division cycle 34
GeneCards (Weizmann)CDC34
Ensembl hg19 (Hinxton)ENSG00000099804 [Gene_View]  chr19:531733-542087 [Contig_View]  CDC34 [Vega]
Ensembl hg38 (Hinxton)ENSG00000099804 [Gene_View]  chr19:531733-542087 [Contig_View]  CDC34 [Vega]
ICGC DataPortalENSG00000099804
TCGA cBioPortalCDC34
AceView (NCBI)CDC34
Genatlas (Paris)CDC34
WikiGenes997
SOURCE (Princeton)CDC34
Genomic and cartography
GoldenPath hg19 (UCSC)CDC34  -     chr19:531733-542087 +  19p13.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CDC34  -     19p13.3   [Description]    (hg38-Dec_2013)
EnsemblCDC34 - 19p13.3 [CytoView hg19]  CDC34 - 19p13.3 [CytoView hg38]
Mapping of homologs : NCBICDC34 [Mapview hg19]  CDC34 [Mapview hg38]
OMIM116948   
Gene and transcription
Genbank (Entrez)AK291554 BC002332 BC009850 BC018143 BC023979
RefSeq transcript (Entrez)NM_004359
RefSeq genomic (Entrez)NC_000019 NC_018930 NT_011295 NW_004929412
Consensus coding sequences : CCDS (NCBI)CDC34
Cluster EST : UnigeneHs.514997 [ NCBI ]
CGAP (NCI)Hs.514997
Alternative Splicing : Fast-db (Paris)GSHG0014397
Alternative Splicing GalleryENSG00000099804
Gene ExpressionCDC34 [ NCBI-GEO ]   CDC34 [ EBI - ARRAY_EXPRESS ]   CDC34 [ SEEK ]   CDC34 [ MEM ]
Gene Expression Viewer (FireBrowse)CDC34 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
BioGPS (Tissue expression)997
Protein : pattern, domain, 3D structure
UniProt/SwissProtP49427 (Uniprot)
NextProtP49427  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP49427
Splice isoforms : SwissVarP49427 (Swissvar)
PhosPhoSitePlusP49427
Domaine pattern : Prosite (Expaxy)UBIQUITIN_CONJUGAT_1 (PS00183)    UBIQUITIN_CONJUGAT_2 (PS50127)   
Domains : Interpro (EBI)UBQ-conjugat_E2    UBQ-conjugating_AS    UBQ-conjugating_enzyme/RWD   
Domain families : Pfam (Sanger)UQ_con (PF00179)   
Domain families : Pfam (NCBI)pfam00179   
DMDM Disease mutations997
Blocks (Seattle)CDC34
PDB (SRS)2OB4    3RZ3    4MDK   
PDB (PDBSum)2OB4    3RZ3    4MDK   
PDB (IMB)2OB4    3RZ3    4MDK   
PDB (RSDB)2OB4    3RZ3    4MDK   
Structural Biology KnowledgeBase2OB4    3RZ3    4MDK   
SCOP (Structural Classification of Proteins)2OB4    3RZ3    4MDK   
CATH (Classification of proteins structures)2OB4    3RZ3    4MDK   
SuperfamilyP49427
Human Protein AtlasENSG00000099804
Peptide AtlasP49427
HPRD00306
IPIIPI00027120   
Protein Interaction databases
DIP (DOE-UCLA)P49427
IntAct (EBI)P49427
FunCoupENSG00000099804
BioGRIDCDC34
STRING (EMBL)CDC34
ZODIACCDC34
Ontologies - Pathways
QuickGOP49427
Ontology : AmiGOG1/S transition of mitotic cell cycle  protein polyubiquitination  ubiquitin-protein transferase activity  ubiquitin-protein transferase activity  protein binding  ATP binding  nucleus  nucleoplasm  cytoplasm  cytoplasm  DNA replication initiation  cellular protein modification process  protein ubiquitination  protein ubiquitination  ubiquitin protein ligase binding  cellular response to interferon-beta  proteasome-mediated ubiquitin-dependent protein catabolic process  positive regulation of neuron apoptotic process  negative regulation of cAMP-mediated signaling  ubiquitin protein ligase activity  ubiquitin conjugating enzyme activity  response to growth factor  protein K48-linked ubiquitination  positive regulation of inclusion body assembly  
Ontology : EGO-EBIG1/S transition of mitotic cell cycle  protein polyubiquitination  ubiquitin-protein transferase activity  ubiquitin-protein transferase activity  protein binding  ATP binding  nucleus  nucleoplasm  cytoplasm  cytoplasm  DNA replication initiation  cellular protein modification process  protein ubiquitination  protein ubiquitination  ubiquitin protein ligase binding  cellular response to interferon-beta  proteasome-mediated ubiquitin-dependent protein catabolic process  positive regulation of neuron apoptotic process  negative regulation of cAMP-mediated signaling  ubiquitin protein ligase activity  ubiquitin conjugating enzyme activity  response to growth factor  protein K48-linked ubiquitination  positive regulation of inclusion body assembly  
Pathways : BIOCARTACell Cycle: G2/M Checkpoint [Genes]    Cyclin E Destruction Pathway [Genes]    E2F1 Destruction Pathway [Genes]   
Pathways : KEGGUbiquitin mediated proteolysis    Herpes simplex infection   
NDEx Network
Atlas of Cancer Signalling NetworkCDC34
Wikipedia pathwaysCDC34
Orthology - Evolution
OrthoDB997
GeneTree (enSembl)ENSG00000099804
Phylogenetic Trees/Animal Genes : TreeFamCDC34
Homologs : HomoloGeneCDC34
Homology/Alignments : Family Browser (UCSC)CDC34
Gene fusions - Rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerCDC34 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CDC34
dbVarCDC34
ClinVarCDC34
1000_GenomesCDC34 
Exome Variant ServerCDC34
ExAC (Exome Aggregation Consortium)CDC34 (select the gene name)
SNP (GeneSNP Utah)CDC34
SNP : HGBaseCDC34
Genetic variants : HAPMAPCDC34
Genomic Variants (DGV)CDC34 [DGVbeta]
Mutations
ICGC Data PortalCDC34 
TCGA Data PortalCDC34 
Broad Tumor PortalCDC34
OASIS PortalCDC34 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCDC34 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CDC34
DgiDB (Drug Gene Interaction Database)CDC34
DoCM (Curated mutations)CDC34 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CDC34 (select a term)
intoGenCDC34
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)19:531733-542087
CONAN: Copy Number AnalysisCDC34 
Mutations and Diseases : HGMDCDC34
OMIM116948   
MedgenCDC34
Genetic Testing Registry CDC34
NextProtP49427 [Medical]
TSGene997
GENETestsCDC34
Huge Navigator CDC34 [HugePedia]  CDC34 [HugeCancerGEM]
snp3D : Map Gene to Disease997
BioCentury BCIQCDC34
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD997
Chemical/Pharm GKB GenePA26265
Clinical trialCDC34
Miscellaneous
canSAR (ICR)CDC34 (select the gene name)
Probes
Litterature
PubMed140 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCDC34
GoPubMedCDC34
iHOPCDC34
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Sat Apr 16 17:39:24 CEST 2016

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