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CDC34 (cell division cycle 34)

Identity

Other namesE2-CDC34
UBC3
UBCH3
UBE2R1
HGNC (Hugo) CDC34
LocusID (NCBI) 997
Atlas_Id 40010
Location 19p13.3
Location_base_pair Starts at 531733 and ends at 542087 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)CDC34   1734
Cards
Entrez_Gene (NCBI)CDC34  997  cell division cycle 34
GeneCards (Weizmann)CDC34
Ensembl hg19 (Hinxton)ENSG00000099804 [Gene_View]  chr19:531733-542087 [Contig_View]  CDC34 [Vega]
Ensembl hg38 (Hinxton)ENSG00000099804 [Gene_View]  chr19:531733-542087 [Contig_View]  CDC34 [Vega]
ICGC DataPortalENSG00000099804
TCGA cBioPortalCDC34
AceView (NCBI)CDC34
Genatlas (Paris)CDC34
WikiGenes997
SOURCE (Princeton)CDC34
Genomic and cartography
GoldenPath hg19 (UCSC)CDC34  -     chr19:531733-542087 +  19p13.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CDC34  -     19p13.3   [Description]    (hg38-Dec_2013)
EnsemblCDC34 - 19p13.3 [CytoView hg19]  CDC34 - 19p13.3 [CytoView hg38]
Mapping of homologs : NCBICDC34 [Mapview hg19]  CDC34 [Mapview hg38]
OMIM116948   
Gene and transcription
Genbank (Entrez)AK291554 BC002332 BC009850 BC018143 BC023979
RefSeq transcript (Entrez)NM_004359
RefSeq genomic (Entrez)NC_000019 NC_018930 NT_011295 NW_004929412
Consensus coding sequences : CCDS (NCBI)CDC34
Cluster EST : UnigeneHs.514997 [ NCBI ]
CGAP (NCI)Hs.514997
Alternative Splicing : Fast-db (Paris)GSHG0014397
Alternative Splicing GalleryENSG00000099804
Gene ExpressionCDC34 [ NCBI-GEO ]     CDC34 [ SEEK ]   CDC34 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP49427 (Uniprot)
NextProtP49427  [Medical]  [Publications]
With graphics : InterProP49427
Splice isoforms : SwissVarP49427 (Swissvar)
Catalytic activity : Enzyme6.3.2.19 [ Enzyme-Expasy ]   6.3.2.196.3.2.19 [ IntEnz-EBI ]   6.3.2.19 [ BRENDA ]   6.3.2.19 [ KEGG ]   
Domaine pattern : Prosite (Expaxy)UBIQUITIN_CONJUGAT_1 (PS00183)    UBIQUITIN_CONJUGAT_2 (PS50127)   
Domains : Interpro (EBI)UBQ-conjugat_E2    UBQ-conjugating_AS    UBQ-conjugating_enzyme/RWD   
Related proteins : CluSTrP49427
Domain families : Pfam (Sanger)UQ_con (PF00179)   
Domain families : Pfam (NCBI)pfam00179   
DMDM Disease mutations997
Blocks (Seattle)P49427
PDB (SRS)2OB4    3RZ3    4MDK   
PDB (PDBSum)2OB4    3RZ3    4MDK   
PDB (IMB)2OB4    3RZ3    4MDK   
PDB (RSDB)2OB4    3RZ3    4MDK   
Human Protein AtlasENSG00000099804
Peptide AtlasP49427
HPRD00306
IPIIPI00027120   
Protein Interaction databases
DIP (DOE-UCLA)P49427
IntAct (EBI)P49427
FunCoupENSG00000099804
BioGRIDCDC34
IntegromeDBCDC34
STRING (EMBL)CDC34
Ontologies - Pathways
QuickGOP49427
Ontology : AmiGOG1/S transition of mitotic cell cycle  protein polyubiquitination  ubiquitin-protein transferase activity  ubiquitin-protein transferase activity  protein binding  ATP binding  nucleus  nucleoplasm  cytoplasm  DNA replication initiation  cellular protein modification process  protein ubiquitination  protein ubiquitination  ligase activity  ubiquitin-like protein transferase activity  ubiquitin protein ligase binding  proteasome-mediated ubiquitin-dependent protein catabolic process  positive regulation of neuron apoptotic process  negative regulation of cAMP-mediated signaling  ubiquitin protein ligase activity  ubiquitin conjugating enzyme activity  response to growth factor  protein K48-linked ubiquitination  positive regulation of inclusion body assembly  
Ontology : EGO-EBIG1/S transition of mitotic cell cycle  protein polyubiquitination  ubiquitin-protein transferase activity  ubiquitin-protein transferase activity  protein binding  ATP binding  nucleus  nucleoplasm  cytoplasm  DNA replication initiation  cellular protein modification process  protein ubiquitination  protein ubiquitination  ligase activity  ubiquitin-like protein transferase activity  ubiquitin protein ligase binding  proteasome-mediated ubiquitin-dependent protein catabolic process  positive regulation of neuron apoptotic process  negative regulation of cAMP-mediated signaling  ubiquitin protein ligase activity  ubiquitin conjugating enzyme activity  response to growth factor  protein K48-linked ubiquitination  positive regulation of inclusion body assembly  
Pathways : BIOCARTACell Cycle: G2/M Checkpoint [Genes]    Cyclin E Destruction Pathway [Genes]    E2F1 Destruction Pathway [Genes]   
Pathways : KEGGUbiquitin mediated proteolysis    Herpes simplex infection   
Protein Interaction DatabaseCDC34
DoCM (Curated mutations)CDC34
Wikipedia pathwaysCDC34
Gene fusion - Rearrangements
Gene fusion: TCGA
Polymorphisms : SNP, variants
NCBI Variation ViewerCDC34 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CDC34
dbVarCDC34
ClinVarCDC34
1000_GenomesCDC34 
Exome Variant ServerCDC34
SNP (GeneSNP Utah)CDC34
SNP : HGBaseCDC34
Genetic variants : HAPMAPCDC34
Genomic Variants (DGV)CDC34 [DGVbeta]
Mutations
ICGC Data PortalCDC34 
TCGA Data PortalCDC34 
Tumor PortalCDC34
Somatic Mutations in Cancer : COSMICCDC34 
LOVD (Leiden Open Variation Database)genes/CDC34
LOVD (Leiden Open Variation Database)genes/CDC34
LOVD (Leiden Open Variation Database)genes/CDC34
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)19:531733-542087
CONAN: Copy Number AnalysisCDC34 
Mutations and Diseases : HGMDCDC34
OMIM116948   
MedgenCDC34
NextProtP49427 [Medical]
GENETestsCDC34
Disease Genetic AssociationCDC34
Huge Navigator CDC34 [HugePedia]  CDC34 [HugeCancerGEM]
snp3D : Map Gene to Disease997
DGIdb (Drug Gene Interaction db)CDC34
BioCentury BCIQCDC34
General knowledge
Homologs : HomoloGeneCDC34
Homology/Alignments : Family Browser (UCSC)CDC34
Phylogenetic Trees/Animal Genes : TreeFamCDC34
Chemical/Protein Interactions : CTD997
Chemical/Pharm GKB GenePA26265
Clinical trialCDC34
Cancer Resource (Charite)ENSG00000099804
Other databases
Probes
Litterature
PubMed138 Pubmed reference(s) in Entrez
CoreMineCDC34
GoPubMedCDC34
iHOPCDC34
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated02-2015Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri May 29 18:16:48 CEST 2015

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