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CDC34 (cell division cycle 34)

Identity

Other namesE2-CDC34
UBC3
UBCH3
UBE2R1
HGNC (Hugo) CDC34
LocusID (NCBI) 997
Location 19p13.3
Location_base_pair Starts at 531733 and ends at 542087 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)CDC34   1734
Cards
Entrez_Gene (NCBI)CDC34  997  cell division cycle 34
GeneCards (Weizmann)CDC34
Ensembl (Hinxton)ENSG00000099804 [Gene_View]  chr19:531733-542087 [Contig_View]  CDC34 [Vega]
ICGC DataPortalENSG00000099804
cBioPortalCDC34
AceView (NCBI)CDC34
Genatlas (Paris)CDC34
WikiGenes997
SOURCE (Princeton)NM_004359
Genomic and cartography
GoldenPath (UCSC)CDC34  -  19p13.3   chr19:531733-542087 +  19p13.3   [Description]    (hg19-Feb_2009)
EnsemblCDC34 - 19p13.3 [CytoView]
Mapping of homologs : NCBICDC34 [Mapview]
OMIM116948   
Gene and transcription
Genbank (Entrez)AK291554 BC002332 BC009850 BC018143 BC023979
RefSeq transcript (Entrez)NM_004359
RefSeq genomic (Entrez)AC_000151 NC_000019 NC_018930 NT_011295 NW_001838476 NW_004929412
Consensus coding sequences : CCDS (NCBI)CDC34
Cluster EST : UnigeneHs.514997 [ NCBI ]
CGAP (NCI)Hs.514997
Alternative Splicing : Fast-db (Paris)GSHG0014397
Alternative Splicing GalleryENSG00000099804
Gene ExpressionCDC34 [ NCBI-GEO ]     CDC34 [ SEEK ]   CDC34 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP49427 (Uniprot)
NextProtP49427  [Medical]
With graphics : InterProP49427
Splice isoforms : SwissVarP49427 (Swissvar)
Catalytic activity : Enzyme6.3.2.19 [ Enzyme-Expasy ]   6.3.2.196.3.2.19 [ IntEnz-EBI ]   6.3.2.19 [ BRENDA ]   6.3.2.19 [ KEGG ]   
Domaine pattern : Prosite (Expaxy)UBIQUITIN_CONJUGAT_1 (PS00183)    UBIQUITIN_CONJUGAT_2 (PS50127)   
Domains : Interpro (EBI)UBQ-conjugat_E2 [organisation]   UBQ-conjugating_AS [organisation]   UBQ-conjugating_enzyme/RWD [organisation]  
Related proteins : CluSTrP49427
Domain families : Pfam (Sanger)UQ_con (PF00179)   
Domain families : Pfam (NCBI)pfam00179   
DMDM Disease mutations997
Blocks (Seattle)P49427
PDB (SRS)2OB4    3RZ3    4MDK   
PDB (PDBSum)2OB4    3RZ3    4MDK   
PDB (IMB)2OB4    3RZ3    4MDK   
PDB (RSDB)2OB4    3RZ3    4MDK   
Human Protein AtlasENSG00000099804 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasP49427
HPRD00306
IPIIPI00027120   
Protein Interaction databases
DIP (DOE-UCLA)P49427
IntAct (EBI)P49427
FunCoupENSG00000099804
BioGRIDCDC34
InParanoidP49427
Interologous Interaction database P49427
IntegromeDBCDC34
STRING (EMBL)CDC34
Ontologies - Pathways
Ontology : AmiGOG1/S transition of mitotic cell cycle  protein polyubiquitination  ubiquitin-protein transferase activity  ubiquitin-protein transferase activity  protein binding  ATP binding  nucleus  nucleus  nucleolus  cytoplasm  DNA replication initiation  cellular protein modification process  protein ubiquitination  protein ubiquitination  acid-amino acid ligase activity  proteasome-mediated ubiquitin-dependent protein catabolic process  positive regulation of neuron apoptotic process  negative regulation of cAMP-mediated signaling  response to growth factor  protein K48-linked ubiquitination  positive regulation of inclusion body assembly  
Ontology : EGO-EBIG1/S transition of mitotic cell cycle  protein polyubiquitination  ubiquitin-protein transferase activity  ubiquitin-protein transferase activity  protein binding  ATP binding  nucleus  nucleus  nucleolus  cytoplasm  DNA replication initiation  cellular protein modification process  protein ubiquitination  protein ubiquitination  acid-amino acid ligase activity  proteasome-mediated ubiquitin-dependent protein catabolic process  positive regulation of neuron apoptotic process  negative regulation of cAMP-mediated signaling  response to growth factor  protein K48-linked ubiquitination  positive regulation of inclusion body assembly  
Pathways : BIOCARTACell Cycle: G2/M Checkpoint [Genes]    Cyclin E Destruction Pathway [Genes]    E2F1 Destruction Pathway [Genes]   
Pathways : KEGGUbiquitin mediated proteolysis    Herpes simplex infection   
Protein Interaction DatabaseCDC34
Wikipedia pathwaysCDC34
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)CDC34
snp3D : Map Gene to Disease997
SNP (GeneSNP Utah)CDC34
SNP : HGBaseCDC34
Genetic variants : HAPMAPCDC34
Exome VariantCDC34
1000_GenomesCDC34 
ICGC programENSG00000099804 
Somatic Mutations in Cancer : COSMICCDC34 
CONAN: Copy Number AnalysisCDC34 
Mutations and Diseases : HGMDCDC34
Mutations and Diseases : intOGenCDC34
Genomic VariantsCDC34  CDC34 [DGVbeta]
dbVarCDC34
ClinVarCDC34
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM116948   
MedgenCDC34
GENETestsCDC34
Disease Genetic AssociationCDC34
Huge Navigator CDC34 [HugePedia]  CDC34 [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneCDC34
Homology/Alignments : Family Browser (UCSC)CDC34
Phylogenetic Trees/Animal Genes : TreeFamCDC34
Chemical/Protein Interactions : CTD997
Chemical/Pharm GKB GenePA26265
Clinical trialCDC34
Cancer Resource (Charite)ENSG00000099804
Other databases
Probes
Litterature
PubMed126 Pubmed reference(s) in Entrez
CoreMineCDC34
iHOPCDC34
OncoSearchCDC34
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 22 18:43:30 CEST 2014

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