Identity
HGNC
LOCATION
6p21.1
LOCUSID
ALIAS
CDC5,CDC5-LIKE,CEF1,PCDC5RP,dJ319D22.1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 988
MIM: 602868
HGNC: 1743
Ensembl: ENSG00000096401
Variants:
dbSNP: 988
ClinVar: 988
TCGA: ENSG00000096401
COSMIC: CDC5L
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000096401 | ENST00000371477 | Q99459 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA445218 | Pancreatic Neoplasms | Disease | ClinicalAnnotation | associated | PD | 22838950 | |
| PA449748 | gemcitabine | Chemical | ClinicalAnnotation | associated | PD | 22838950 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34298017 | 2021 | CDC5L promotes early chondrocyte differentiation and proliferation by modulating pre-mRNA splicing of SOX9, COL2A1, and WEE1. | 6 |
| 34903139 | 2021 | Downregulation of DEAD-box helicase 21 (DDX21) inhibits proliferation, cell cycle, and tumor growth in colorectal cancer via targeting cell division cycle 5-like (CDC5L). | 3 |
| 34298017 | 2021 | CDC5L promotes early chondrocyte differentiation and proliferation by modulating pre-mRNA splicing of SOX9, COL2A1, and WEE1. | 6 |
| 34903139 | 2021 | Downregulation of DEAD-box helicase 21 (DDX21) inhibits proliferation, cell cycle, and tumor growth in colorectal cancer via targeting cell division cycle 5-like (CDC5L). | 3 |
| 32526706 | 2020 | ANXA7 promotes the cell cycle, proliferation and cell adhesion-mediated drug resistance of multiple myeloma cells by up-regulating CDC5L. | 7 |
| 32526706 | 2020 | ANXA7 promotes the cell cycle, proliferation and cell adhesion-mediated drug resistance of multiple myeloma cells by up-regulating CDC5L. | 7 |
| 29871935 | 2018 | Oncogenic Properties of NEAT1 in Prostate Cancer Cells Depend on the CDC5L-AGRN Transcriptional Regulation Circuit. | 53 |
| 29871935 | 2018 | Oncogenic Properties of NEAT1 in Prostate Cancer Cells Depend on the CDC5L-AGRN Transcriptional Regulation Circuit. | 53 |
| 28387715 | 2017 | Prp19 Arrests Cell Cycle via Cdc5L in Hepatocellular Carcinoma Cells. | 10 |
| 28387715 | 2017 | Prp19 Arrests Cell Cycle via Cdc5L in Hepatocellular Carcinoma Cells. | 10 |
| 26490980 | 2016 | Expression of CDC5L is associated with tumor progression in gliomas. | 14 |
| 26553251 | 2016 | Expression and Clinical Role of Cdc5L as a Novel Cell Cycle Protein in Hepatocellular Carcinoma. | 15 |
| 26490980 | 2016 | Expression of CDC5L is associated with tumor progression in gliomas. | 14 |
| 26553251 | 2016 | Expression and Clinical Role of Cdc5L as a Novel Cell Cycle Protein in Hepatocellular Carcinoma. | 15 |
| 26130721 | 2015 | CTNNBL1 facilitates the association of CWC15 with CDC5L and is required to maintain the abundance of the Prp19 spliceosomal complex. | 7 |
Citation
Dessen P
CDC5L (cell division cycle 5 like)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43199/cdc5l
