CDHR3 (cadherin related family member 3)

2014-11-01  

Identity

HGNC
CDHR3
LOCATION
7q22.3
LOCUSID
222256
ALIAS
CDH28
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 222256
MIM: 615610
HGNC: 26308
Ensembl: ENSG00000128536

Variants:

dbSNP: 222256
ClinVar: 222256
TCGA: ENSG00000128536
COSMIC: CDHR3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000128536ENST00000317716Q6ZTQ4
ENSG00000128536ENST00000466045H7C555
ENSG00000128536ENST00000468477H7C548
ENSG00000128536ENST00000478080E7EQG5
ENSG00000128536ENST00000488386F8WF00
ENSG00000128536ENST00000496633E9PEI5

Expression (GTEx)

0
5
10
15
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
242415372014A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations.152
258480092015Cadherin-related family member 3, a childhood asthma susceptibility gene product, mediates rhinovirus C binding and replication.130
291214792018Cadherin-related Family Member 3 Genetics and Rhinovirus C Respiratory Illnesses.23
306598172019Rhinoviruses and Their Receptors.9
262707392015Rhinovirus in the Pathogenesis and Clinical Course of Asthma.8
283188852017Genetic association of the functional CDHR3 genotype with early-onset adult asthma in Japanese populations.6
309301752019Functional genomics of CDHR3 confirms its role in HRV-C infection and childhood asthma exacerbations.6
279235632017Association between the CDHR3 rs6967330 risk allele and chronic rhinosinusitis.5
287826312017CDHR3 gene variation and childhood bronchiolitis.5
309169892019CDHR3 Asthma-Risk Genotype Affects Susceptibility of Airway Epithelium to Rhinovirus C Infections.3

Citation

Dessen P

CDHR3 (cadherin related family member 3)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/61651/cdhr3