CDK2AP1 (cyclin dependent kinase 2 associated protein 1)

2003-02-01  

Identity

HGNC
LOCATION
12q24.31
LOCUSID
ALIAS
DOC1,DORC1,ST19,doc-1,p12DOC-1
FUSION GENES

Other Information

Locus ID:

NCBI: 8099
MIM: 602198
HGNC: 14002
Ensembl: ENSG00000111328

Variants:

dbSNP: 8099
ClinVar: 8099
TCGA: ENSG00000111328
COSMIC: CDK2AP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000111328ENST00000261692O14519
ENSG00000111328ENST00000535796F5GZF0
ENSG00000111328ENST00000535979O14519
ENSG00000111328ENST00000538446O14519
ENSG00000111328ENST00000542174O14519
ENSG00000111328ENST00000544658O14519
ENSG00000111328ENST00000618072O14519
ENSG00000111328ENST00000652466O14519

Expression (GTEx)

0
50
100
150

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
372174932023The deleted in oral cancer (DOC1 aka CDK2AP1) tumor suppressor gene is downregulated in oral squamous cell carcinoma by multiple microRNAs.0
372174932023The deleted in oral cancer (DOC1 aka CDK2AP1) tumor suppressor gene is downregulated in oral squamous cell carcinoma by multiple microRNAs.0
363621152022The Association between Cyclin Dependent Kinase 2 Associated Protein 1 (CDK2AP1) and Molecular Subtypes of Lethal Prostate Cancer.0
363621152022The Association between Cyclin Dependent Kinase 2 Associated Protein 1 (CDK2AP1) and Molecular Subtypes of Lethal Prostate Cancer.0
297343532018Knockdown of CDK2AP1 in human embryonic stem cells reduces the threshold of differentiation.2
303432782018mRNA Expression of CDK2AP1 in Human Breast Cancer: Correlation with Clinical and Pathological Parameters.4
297343532018Knockdown of CDK2AP1 in human embryonic stem cells reduces the threshold of differentiation.2
303432782018mRNA Expression of CDK2AP1 in Human Breast Cancer: Correlation with Clinical and Pathological Parameters.4
286833242017DOC1-Dependent Recruitment of NURD Reveals Antagonism with SWI/SNF during Epithelial-Mesenchymal Transition in Oral Cancer Cells.33
286833242017DOC1-Dependent Recruitment of NURD Reveals Antagonism with SWI/SNF during Epithelial-Mesenchymal Transition in Oral Cancer Cells.33
273492082016p12CDK2-AP1 interacts with CD82 to regulate the proliferation and survival of human oral squamous cell carcinoma cells.3
273492082016p12CDK2-AP1 interacts with CD82 to regulate the proliferation and survival of human oral squamous cell carcinoma cells.3
257858332015Knockdown of CDK2AP1 in primary human fibroblasts induces p53 dependent senescence.6
257858332015Knockdown of CDK2AP1 in primary human fibroblasts induces p53 dependent senescence.6
246209592014Knockdown of CDK2AP1 by RNA interference inhibits cell growth and tumorigenesis of human glioma.4

Citation

Dessen P

CDK2AP1 (cyclin dependent kinase 2 associated protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/40032/cdk2ap1